Abacterial Pyuria and Reiter's Syndrome

Abstract

PENICILLIN IN THE TREATMENT OF INFECTED HANDS MEDBCRATS ORNA605well as in man-hours. Even better results would be obtainable if patients could be seen in the earlier stages of infection. Of the cases detailed in Table I, 65% needed immediate incision; in the three cases in Table II The penicillin-treated series comprised 7 cases of paronychia and pulp-space infection, with an average loss of 9.9 days' duty; 6 cases of tenosynovitis, with an average loss of 9.9 days (excluding Case 13, 7.4 days); and 4 cases of palmar-space infection, with an average loss of 17 days (excluding Case 16, 9.3 days). The average loss of duty in these 17 cases was 10.9 days. If the two unusual cases, Nos. 13 and 16, are excluded, the final average is reduced to 8.9 days-a saving of 56% compared with the non-penicillin series.On the basis of these results it is suggested that the administration of penicillin in all severe infections of the hand, both in the early stages and after any necessary surgical intervention, should be adopted as a routine method of treatment.In practice a dosage of 125,000 units in oil or 300,000 units in aqueous solution twice daily has been found adequate.We are indebted to Mr. G. T. Mullally, Senior Surgeon, Westminster Hospital, whose enthusiasm and interest made this experiment possible; to Prof. R. J. V. Pulvertaft, who made penicillin in beeswax-oil available at a time when supplies were limited; and to the nursing staff of the surgery for their co-operation in carrying out treatment.

Value if Treatment in Reiter'S Disease

“…It is also the general opinion that arsenical therapy is of little value, although it has been claimed that this treatment has a beneficial effect on the bladder condition at times (Baines, 1947). The results obtained with streptomycin and the wide-spectrum antibiotics by authors already mentioned and by Warthin (1948), Dienes, Ropes, Smith, Madoff, and Bauer (1948), Coodley, Weiss, and Egeberg (1948), Willcox and Findlay (1952a, b), and Wheatley (1953) are shown in Table III.…”

Sterile Non-Tuberculous Pyuria1

“…Sometimes the symptoms of cystitis are preceded by a sterile urethral discharge (Donovan, 1946;Peters, 1946;Vassallo, 1946;Baines, 1947;Horne, 1953) and there is evidence that the condition is sometimes associated with Reiter's syndrome (Goldstein, 1947).…”

Microbiological Studies of Reiter'S Disease

“…It has, however, been clearly established that, whereas PPLO can rarely be cultured from the genital tract of prepubertal males, they occur not infrequently in normal women and are common in both males and females with a variety of genito-urinary disorders. In recent years, also, a possible virus aetiology of Reiter's disease has been conjectured (Harkness, 1945(Harkness, , 1947Baines, 1947;Coutts, 1947;Short, 1947;Dunham, Rock, and Bell, 1947;Hall and Finegold, 1953;Robinson and 11 others, 1953;Willcox, 1957;Mavroglu, 1958;Burgess, 1959). Visualization of inclusion bodies (Harkness, 1945(Harkness, , 1947 or isolation of viruses (Baines, 1947;Dunham and others, 1947;Robinson and others, 1953) have been claimed in some reports, but Ford (1956Ford ( , 1958 obtained only negative results.…”