Ab1562 nail Fold Capillaroscopy in Evaluating Interstitial Lung Disease of Rheumatoid Arthritis, Systemic Sclerosis and Idiopathic Type

Abstract

BackgroundNail fold capillaroscopy (NFC) is a non invasive diagnostic tool to detect early changes of microcirculation of different collagen diseases as rheumatoid arthritis associated interstitial lung disease (RA-ILD), systemic sclerosis interstitial lung disease (SS-ILD) and idiopathic ILD (Ting et al., 2020).ObjectivesThe study aimed to evaluate role of NFC in RA-ILD, SS-ILD and idiopathic ILD, and to determine if there is a correlation of it to disease activity.MethodsA case control study conducted on 100 patients with ILD, where 30 patients with RA-ILD, 30 patients with SS-ILD and 40 patients with idiopathic-ILD, fulfilling ACR/EULAR criteria, 2013. They were examined clinically and radiologicaly. Pulmonary function tests (PFT) and NFC were done.ResultsPleural irregularities were found in 42% of RA-ILD, 30% of SS-ILD where subpleural irregularities were found in 31% of RA-ILD and 46.7% of SS-ILD. Ground glass opacity was in 13% of RA-ILD, 76.7% in SS-ILD and70% in idiopathic –ILD. Honeycomb appearance was in 11.5% of RA-ILD, 30% in SSILD and 65% of idiopathic ILD.SS-ILD showed the highest capillary changes especially patients with pneumonia. A significant correlation was found between NFC and PFT in idiopathic-ILD.ConclusionNFC is a sensitive and specific adjuvant tool in monitoring micro vascular changes in rheumatologic diseases and can be used as assessment tool in severity of the disease.Reference[1]Ting Z, Lin F and Chen H (2020): Pattern of NFC in patients with SLE. Archives of Rheumatology, 35(4), 568Acknowledgements:NIL.Disclosure of InterestsNone Declared.