Abstract:BackgroundThe introduction of new drugs, in particular tumour necrosis factor inhibitor (TNFi) has revolutionized the treatment of spondyloarthritis (SpA). Meanwhile, about 30% of patients do not react to first-line TNFi. To date,there is no recommendations available forthe treatment of SpA patients after first TNFi failure.ObjectivesIn this study we assessed the effectiveness of a second and third biotherapy in patients with SpA with an inadequate response to previous TNFi and to analyze the survival of the s… Show more
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