Abstract:ObjectivesB subsets. To study the correlation between the counts of B cell subsets and SLE activity, and their dynamics after treatment with rituximab.MethodsRituximab in doses from 500 to 2000 mg was administered to 8 SLE patients with high and moderate disease activity (1 male and 7 females), 6 patients had lupus nephritis. The relative counts of CD19 + B cells, the total population of memory B cells (CD19 + CD27 +), “preswitch” (CD19 + IgD + CD27 +) and “postswitch” (CD19 + IgD-CD27 +) memory B cells, naive… Show more
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