2022
DOI: 10.1136/annrheumdis-2022-eular.16
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Ab0449 the Prevalence of Autoantibodies Against Ifnα Is High in Sle and Associated With a High Frequency of Tuberculosis

Abstract: BackgroundIFNα and anti-IFNα autoantibodies have been implicated in susceptibility both for systemic lupus erythematosus (SLE) and viral infection.ObjectivesWe aimed to analyze the SLE disease phenotype and risk for infection associated with anti-IFN-α IgG autoantibodies in SLE patientsMethodsIn this multidisciplinary retrospective single referral center study, all consecutive patients with SLE admitted between January 1st and November 30th 2020 were considered. All subjects fulfilled the ACR/EULAR 2019 criter… Show more

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