Abstract:Background
The etiology of rheumatoid arthritis (R.A.), an autoimmune, polygenic, inflammatory disease, has not yet been clarified despite the intense research1. In addition to its more commonly known metabolic effects such as those associated with calcium homeostasis, vitamin D has, in general, suppressive effects on the immune system, especially on T helper cell function. T cells are critical in the development of autoimmune reactions and autoimmune diseases. Low vitamin D levels have been associated with th… Show more
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