Abstract:BackgroundReactive oxygen species accumulation and iron overload are involved in the pathogenesis of rheumatoid arthritis (RA). Ferroptosis, as a non-apoptotic form of programmed cell death, characteristically depends on iron and lipid peroxidation. However, the role of ferroptosis in RA has not been explored.ObjectivesTo explore the role of ferroptosis in immune imbalance of rheumatoid arthritis.MethodsIron content in synovial fluid was determined by colorimetry. Lipid peroxidation was assessed by flow cytome… Show more
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