Abstract:Background
The Delta/Notch like EGF-related receptor (DNER) is a single-pass transmembrane protein with characteristic EGF-like repeats in the extracellular domain, similar to those of the Notch receptor and its ligand Delta. DNER is an activator of the Notch signaling pathway, which plays a major role in cell fate determination and differentiation. In our previous study, an overexpression of DNER was observed in lesional areas of human osteoarthritic articular cartilage when compared to unaffected zones of th… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.