AB₂ Y-shaped miktoarm star conductive polyaniline-modified poly(ethylene glycol) and its electrospun nanofiber blend with poly(ε-caprolactone)

Abstract

This paper describes the synthesis and characterization of novel type AB 2 Y-shaped miktoarm star conductive polyaniline-modified poly(ethylene glycol) [PEG-b-(PANI) 2 ], and preparation of its electrospun nanofiber blend with poly(3-caprolactone) [PEG-b-(PANI) 2 /PCL]. The chemical structures of all samples as representatives were characterized by means of Fourier transform infrared (FTIR), and 1 H nuclear magnetic resonance (NMR) spectroscopies. The molecular weights of PANI segment(s), and miktoarm star conductive PEG-b-(PANI) 2 were found to be 3720, and 5847, respectively, from 1 H NMR spectroscopy. Moreover, electrical conductivities, electroactivities, thermal behaviors, morphologies, and compositions of the synthesized samples were studied. The conductivity and electroactivity measurements showed that PEG-b-(PANI) 2 and PEG-b-(PANI) 2 /PCL electrospun blend nanofibers have lower electrical conductivity and electroactivity than those of the pure PANI. However, the lower electrical conductivity and electroactivity levels in these materials can be improved at the price of solubility, processability, and biocompatibility. Field emission scanning electron microscopy (FE-SEM) images showed that the PEG-b-(PANI) 2 /PCL electrospun nanofibers have a single phase, indicating good interactions between the blend components. The average diameters of these fibers were in the size range of 70 AE 10 nm, and there was no formation of beaded structures in comparison with electrospun fibers of pure PCL. As results, we predicted the synthesized PEG-b-(PANI) 2 and PEG-b-(PANI) 2 /PCL can be used in the biomedical fields such as in conductive scaffolds to promote neurite outgrowth, and nerve regeneration.Scheme 1 Synthetic route of the AB 2 Y-shaped miktoarm star conductive polyaniline-modified poly(ethylene glycol).36718 | RSC Adv., 2015, 5, 36715-36726This journal is

Development of novel electrically conductive scaffold based on hyperbranched polyester and polythiophene for tissue engineering applications

“…The G4‐PTh/PCL nanofibers were prepared by subsequent electrospinning the same volume solutions of G4‐PTh (1% w/v), and PCL (3% w/v) under conditions described in our previous works …”

“…Electrospinning of the G4-PTh and PCL The G4-PTh/PCL nanofibers were prepared by subsequent electrospinning the same volume solutions of G4-PTh (1% w/v), and PCL (3% w/v) under conditions described in our previous works. 30,31 Biocompatibility analysis Cell culture. The mouse osteoblast cells (MC3T3-E1 cell line) was cultured into flasks, and kept in a humidified incubator with 5% CO 2 at 378C.…”

“…The electrospinning is suggested as an efficient approach to prepare biocompatible conductive nanofibers to mimic the architecture and biological functions of the ECM. This technique has attracted a great deal of attention in the past decade for fabrication of conductive scaffolds, mainly due to high porosity, high surface‐to‐volume ratio, ultrathin continuous fibers, adjustable pore size distribution as well as its simplicity and more cost‐effectivity …”

“…This technique has attracted a great deal of attention in the past decade for fabrication of conductive scaffolds, mainly due to high porosity, high surface-to-volume ratio, ultrathin continuous fibers, adjustable pore size distribution as well as its simplicity and more cost-effectivity. 29,30 The objective of the present study is to fabrication of novel three-dimensional (3D), conducting, biocompatible, and porous scaffold composed of hyperbranched aliphatic polyester (HAP), polythiophene (PTh), and poly(e-caprolactone) (PCL) for tissue engineering applications. The morphology, electerical conductivity, mechanical properties, and wettability of the scaffold were studied.…”

Chemical and electrochemical grafting of polyaniline onto poly(vinyl chloride): synthesis, characterization, and materials properties

“…[1][2][3][4][5][6][7] Among various ICPs, polypyrrole (PPy), polythiophene (PTh), and polyaniline (PANI) are promising candidates to incorporate in practical applications, in part because of their enough stability under normal processing conditions and combination of unique physical and chemical processes (e.g., electron and energy transfer). [1,2,8] In this respect, PANI and its derivatives have many advantages over other conducting polymers, such as thermal stability up to 250°C, tunable electroactivity, high electrical conductivity, fast oxidation-reduction reactions, good environmental stability, high energy density, ease of synthesis, and low cost.…”