Abstract:Background and objectives
Early diagnosis and treat-to-target strategies in rheumatoid arthritis (RA) have allowed the achievement of remission in a significant percentage of cases. Despite the possibility of remission maintenance even after treatment suspension, three critical issues remain unsolved: 1) to what extent suppression of inflammation can coincide with reversal of the pathogenic process, 2) the parameters able to predict in which patients treatments can be suspended, 3) the dynamics of relapse. In … Show more
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