A Zinc Coordination Polymer Sensor for Selective and Sensitive Detection of Doxycycline Based on Fluorescence Enhancement

Abstract

In this work, a novel coordination polymer HNU-55 has been synthesized by the reaction of Zn(II) ion with the organic ligand 3-pyridinesulfonic acid (PSA) under solvothermal condition, which can be used as a fluorescent sensor for the detection of doxycycline (DOX). The fluorescent performance is effective in a wide linear range from 0 to 30 μM of DOX with a low detection limit of 3.7 nM. Likewise, the fluorescent sensor presents good selectivity, anti-interference, and circularity. Additionally, the HNU-55 sensor can be successfully used to assay the content of DOX in pig feed. Furthermore, the mechanism of fluorescence enhancement has been discussed in detail, which provides a clear understanding for the antibiotic detection based on the fluorescence enhancement.

Stable bifunctional ZnII-based sensor toward acetylacetone and l-histidine via a fluorescence red shift and turn-on effect

“…The UV–Vis absorption spectra show that there was an obvious change of the absorption band upon the addition of l -His, which revealed that there may exist the interaction between L-His and JXUST-15 . 54 Besides, the shorter average fluorescence lifetime (τ av ) of JXUST-15 @ l -His (5.42 × 10 −3 ms) compared to JXUST-15 (6.07 × 10 −3 ms) also confirmed that there may exist the excited state interaction between l -His and JXUST-15 . 28 In addition, the excited electrons transferred from a high-lying π*-type LUMO to the CB of the complex, which could result in fluorescence enhancement.…”

“…S8a, ESI†), which confirmed the existence of the interaction between acac and JXUST-15 . 54 In addition, the average fluorescence lifetime ( τ av ) was measured to evaluate the excited-state behaviour of JXUST-15 after soaking in acac, which exhibited a biexponential decay, and calculated using the formula τ av = ( A 1 τ 1 2 + A 2 τ 2 2 )/( A 1 τ 1 + A 2 τ 2 ). The fluorescence lifetimes demonstrated that there may exist an excited state interaction between acac and JXUST-15 , 28 because the fluorescence lifetime ( τ av ) of JXUST-15 @acac (5.59 × 10 −3 ms) was shorter than that of JXUST-15 (6.07 × 10 −3 ms) (Fig.…”

Spray drying-assisted construction of hierarchically porous ZIF-8 for controlled release of doxorubicin

“…4e), indicating coordination between the Zn of HP-ZIF-8 and the C–O and CO groups of DOX. 69–71 As for N 1s fitting, the 398.46 eV peak belonged to imidazole linkers, while the 398.97 eV peak was assigned to the Zn–N bond (Fig. 4f).…”

Heteronuclear metal–organic framework‐based fluorescent sensor for the detection of tetracycline antibiotics

“…As shown in the figure, HNU‐61 has no absorbance, and TCY has a maximum absorption wavelength at 367 nm. However, the maximum absorption wavelength of HNU‐61 and TCY mixture is 386 nm, which better proves the interaction between Zn 2+ and TCY when TCY is added, [ 17,18,32 ] and the fluorescence is sensitized by TCs.…”