A young woman with severe bilateral visual loss and putaminal infarcts

Margolin, Edward; Donaldson, Laura

doi:10.1136/practneurol-2022-003407

Cited by 1 publication

(1 citation statement)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[ 13 14 ] Long-term visual impairment has been reported in methanol-poisoned individuals in various studies. [ 15 16 ] These impairments may include peripheral constriction of visual fields and/or central scotoma, reduced VA, loss of color vision, and, in the most severe cases, complete blindness. [ 17 ] Several factors related to poor outcomes and the prediction of optic nerve axonal degeneration following methanol-induced acute optic neuropathy have been previously examined.…”

Section: Introductionmentioning

confidence: 99%

Follow-up of Methanol-related Visual Defects in a Cohort Study: Initial Severity Predicts Long-term Outcome

Gheshlaghi,

Wong,

Firuzfar

et al. 2023

Journal of Research in Pharmacy Practice

View full text Add to dashboard Cite

Objective: Methanol poisoning can occur either intentionally through the consumption of methanol-containing products or accidentally through ingestion, resulting in visual impairment. We assessed the long-term visual sequelae in patients with methanol poisoning. Methods: This prospective cohort study was conducted at referral centers, Khorshid and Alzahra University Hospitals, affiliated with Isfahan University of Medical Sciences, Isfahan, Iran. The study included patients hospitalized for methanol poisoning from June 22, 2018, to June 21, 2020, with follow-up extended until June 2021. Toxico-clinical and ophthalmologic examination data were collected from patients upon hospital admission, discharge, and during follow-up. Findings: Thirty-nine patients were assessed in this study. The majority of them (94.9%) were male, with an average age of 34 years. Patients who presented with reduced visual acuity (VA) upon admission subsequently showed abnormalities (in acuity and visual fields) during follow-up (n = 13). Among the patients who displayed visual field defects on admission, bilateral optic disc atrophy was observed in follow-up (n = 13). Conversely, patients who reported blurred vision, with or without photophobia upon admission, had normal results in their follow-up eye examinations. Among the 36 patients who underwent dialysis, 14 (38.9%) exhibited visual impairment during follow-up examinations. Additionally, 38 patients received sodium bicarbonate, and 14 of them (36.85%) also presented ocular abnormalities. Conclusion: Patients who demonstrated VA deficits upon admission are more likely to experience long-term VA and visual field defects, as well as optic disc atrophy. Patients who solely complained of blurred vision, with or without photophobia, during admission were less likely to develop long-term visual defects.

show abstract