A young male with chest pain, cough and fever

Kapotsis, G.E.; Daniil, Zoe; Malagari, K.; Vamvouka, C.; Kalomenidis, I.; Roussos, Ch.; Papiris, Spyridon

doi:10.1183/09031936.04.00008204

Cited by 5 publications

(3 citation statements)

References 8 publications

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“…Disease due to H. capsulatum is highly endemic in the Midwestern United States, but low-level endemic disease has also been reported in Mexico, Central America, and South America as well as in parts of Southeast Asia (62,121,207,331,383). Infection occurs when H. capsulatum conidia are inhaled, so activities such as mining, speleology, construction, and agriculture are associated with an increased risk of disease (178). Pulmonary infection with H. capsulatum is generally asymptomatic; only an estimated 0.5% of infected persons will develop symptomatic disease (388).…”

Section: Histoplasmosis the Dimorphic Fungusmentioning

confidence: 99%

Cavitary Pulmonary Disease

2008

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SUMMARY A pulmonary cavity is a gas-filled area of the lung in the center of a nodule or area of consolidation and may be clinically observed by use of plain chest radiography or computed tomography. Cavities are present in a wide variety of infectious and noninfectious processes. This review discusses the differential diagnosis of pathological processes associated with lung cavities, focusing on infections associated with lung cavities. The goal is to provide the clinician and clinical microbiologist with an overview of the diseases most commonly associated with lung cavities, with attention to the epidemiology and clinical characteristics of the host.

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Section: Histoplasmosis the Dimorphic Fungusmentioning

confidence: 99%

Cavitary Pulmonary Disease

2008

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“…The most common presentation is acute pulmonary histoplasmosis. 5 Patients typically present with pulmonary symptoms that run a self-limiting course. Chest radiographs may show hilar lymphadenopathy and upper lobe predominant nodules.…”

Section: Fig 1 Supine Chest Radiograph Of the Patient With A Large Pleural Effusion On The Left (Arrow)mentioning

confidence: 99%

Multiple skeletal lesions and pleural effusion owing to Histoplasma capsulatum infection in an immunocompetent patient from a non-endemic region

Suleman

Scheepers²

2011

S. Afr. j. radiol.

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We describe a rare case of multiple skeletal lesions and a pleural effusion owing to Histoplasma capsulatum infection in a 16-year-old immunocompetent girl residing in a non-endemic region. Of note is that the patient had a lesion within a thoracic vertebra. Following an extensive literature search, we found that vertebral involvement by H. capsulatum had not been previously described. Pleural effusion and skeletal lesions are both rare manifestations of H. capsulatum infection.

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“…[2–4] Infection can be acquired by implantation, direct inoculation, or inhalation of spores from contaminated soil and often present as respiratory diseases. [1256] Primary cutaneous presentations in affected persons may be misdiagnosed as cutaneous tumors due to the long duration and nonspecificity of presenting symptoms. Also, the manifestation of these mycoses is dependant on host factors.…”

Section: Introductionmentioning

confidence: 99%

Cutaneous manifestations of deep mycosis: An experience in a tropical pathology laboratory

Samaila

Abdullahi

2011

Indian J Dermatol

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Background:Cutaneous manifestations of deep mycotic infection are fraught with delayed or misdiagnosis from mainly cutaneous neoplastic lesions.Aim:This study is designed to present our experience of these mycoses in a pathology laboratory in the tropics.Materials and Methods:A clinicopathologic analysis of deep mycotic infections was conducted over a 15 years period Formalin fixed and paraffin wax processed biopsies were stained with hematoxylin and eosin, periodic acid Schiff (PAS), and Grocott's methenamine silver (GMS) for the identification of fungus specie. Patients’ bio-data and clinical information were obtained from records.Results:Twenty males and seven females presented with 6 months to 6 years histories of varying symptoms of slow growing facial swellings, nodules, subcutaneous frontal skull swelling, proptosis, nasal blockage, epistaxis, discharging leg sinuses, flank mass, convulsion and pain. Of the 27 patients, four gave antecedent history of trauma, two had recurrent lesions which necessitated maxilectomy, two presented with convulsion without motor dysfunction while one had associated erosion of the small bones of the foot. None of the patients had debilitating illnesses such as diabetes mellitus, tuberculosis, and HIV infection. Tissue histology revealed histoplasmosis (10), mycetoma (9), subcutaneous phycomycosis (6), and phaeohyphomycosis (2).Conclusion:Deep mycoses may present primarily as cutaneous lesions in immunocompetent persons and often elicit distinct histologic inflammatory response characterized by granuloma formation. Diagnosis in resource constraint setting can be achieved with tissue stained with PAS and GMS which identifies implicated fungus. Clinical recognition and adequate knowledge of the pathology of these mycoses may reduce attendant patient morbidity.

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A young male with chest pain, cough and fever

Cited by 5 publications

References 8 publications

Cavitary Pulmonary Disease

Cavitary Pulmonary Disease

Multiple skeletal lesions and pleural effusion owing to Histoplasma capsulatum infection in an immunocompetent patient from a non-endemic region

Cutaneous manifestations of deep mycosis: An experience in a tropical pathology laboratory

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