A woman with purple toes after intrarticular hyaluronic acid administration

Abstract

Intra-articular injected hyaluronic acid provides pain relief and functional improvements in patients with gonarthrosis. We present a 92-year-old woman with iatrogenic blue toe syndrome after intra-articular injection of hyaluronic acid. This is an anecdotally rare complication, which aims to heighten the clinician's awareness on the possible intervention pitfalls and spectrum of therapeutic indications.