A wireless system for gastric slow wave acquisition and gastric electrical stimulation

Lee, Audrey; Wang, Rui; Farajidavar, Aydin

doi:10.1109/biowireless.2016.7445559

Cited by 5 publications

(3 citation statements)

References 7 publications

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“…However, the measured pulses were curved due to the capacitive property of the impedance that is typical in stimulation of the excitable tissue [21]. An example of the measurements for this experiment is available in our previous publication [22].…”

Section: Resultsmentioning

confidence: 99%

A Miniature Configurable Wireless System for Recording Gastric Electrophysiological Activity and Delivering High-Energy Electrical Stimulation

Wang

Abukhalaf

Javan-Khoshkholgh

et al. 2018

IEEE J. Emerg. Sel. Topics Circuits Syst.

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The purpose of this paper is to develop and validate a miniature system that can wirelessly acquire gastric electrical activity called slow waves, and deliver high energy electrical pulses to modulate its activity. The system is composed of a front-end unit, and an external stationary back-end unit that is connected to a computer. The front-end unit contains a recording module with three channels, and a single-channel stimulation module. Commercial off-the-shelf components were used to develop front- and back-end units. A graphical user interface was designed in LabVIEW to process and display the recorded data in real-time, and store the data for off-line analysis. The system was successfully validated on bench top and in vivo in porcine models. The bench-top studies showed an appropriate frequency response for analog conditioning and digitization resolution to acquire gastric slow waves. The system was able to deliver electrical pulses at amplitudes up to 10 mA to a load smaller than 880 Ω. Simultaneous acquisition of the slow waves from all three channels was demonstrated in vivo. The system was able to modulate –by either suppressing or entraining– the slow wave activity. This study reports the first high-energy stimulator that can be controlled wirelessly and integrated into a gastric bioelectrical activity monitoring system. The system can be used for treating functional gastrointestinal disorders.

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Section: Resultsmentioning

confidence: 99%

A Miniature Configurable Wireless System for Recording Gastric Electrophysiological Activity and Delivering High-Energy Electrical Stimulation

Wang

Abukhalaf

Javan-Khoshkholgh

et al. 2018

IEEE J. Emerg. Sel. Topics Circuits Syst.

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“…16 However, as part of its design, wires were passed through the nasal passage of subjects, and although they reported no discomfort, it would not be a feasible solution for long-term use. Several recent studies in wireless implantable gastric monitoring (IGM) have introduced promising devices but have not yet translated to in vivo applications [17][18][19][20][21][22] or validated their measurements using established techniques. 23 There remains a need for a gastric monitoring device suitable for human implantation.…”

Section: Introductionmentioning

confidence: 99%

Translation of an existing implantable cardiac monitoring device for measurement of gastric electrical slow‐wave activity

Dowrick,

Jungbauer Nikolas,

Offutt

et al. 2023

Neurogastroenterology Motil

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BackgroundDespite evidence that slow‐wave dysrhythmia in the stomach is associated with clinical conditions such as gastroparesis and functional dyspepsia, there is still no widely available device for long‐term monitoring of gastric electrical signals. Actionable biomarkers of gastrointestinal health are critically needed, and an implantable slow‐wave monitoring device could aid in the establishment of causal relationships between symptoms and gastric electrophysiology. Recent developments in the area of wireless implantable gastric monitors demonstrate potential, but additional work and validation are required before this potential can be realized.MethodsWe hypothesized that translating an existing implantable cardiac monitoring device, the Reveal LINQ™ (Medtronic), would present a more immediate solution. Following ethical approval and laparotomy in anesthetized pigs (n = 7), a Reveal LINQ was placed on the serosal surface of the stomach, immediately adjacent to a validated flexible‐printed‐circuit (FPC) electrical mapping array. Data were recorded for periods of 7.5 min, and the resultant signal characteristics from the FPC array and Reveal LINQ were compared.Key ResultsThe Reveal LINQ device recorded slow waves in 6/7 subjects with a comparable period (p = 0.69), signal‐to‐noise ratio (p = 0.58), and downstroke width (p = 0.98) to the FPC, but with reduced amplitude (p = 0.024). Qualitatively, the Reveal LINQ slow‐wave signal lacked the prolonged repolarization phase present in the FPC signals.Conclusions & InferencesThese findings suggest that existing cardiac monitors may offer an efficient solution for the long‐term monitoring of slow waves. Translation toward implantation now awaits.

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“…There are several wireless IMDs that are used in some disorder treatments i.e. deep brain neorostimulators (DBS)s, cochlear implants, implantable cardiac defibrillators (ICD)/pacemakers, gastric stimulators, insulin pumps [2][3][4][5][6]. But different wireless IMDs for the different disorder treatments will be possible in the future.…”

Section: Introductionmentioning

confidence: 99%

Determining Threshold Distance Providing Less Interference for Wireless Medical Implant Communication Systems in Coexisting Environments under Shadow Fading Conditions

Kulac

2017

SDÜ Fen Bil Enst Der

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Important interference problems will be able to be encountered especially close areas to the hospitals where wireless implantable medical systems' communication traffic occurs heavily in near future. It is possible that these interferences could cause wireless implant devices to malfunction and harmful effects on patients. In this study, it is proposed to determine threshold distance in order to get less interference for wireless implantable medical systems under shadow fading conditions where MICS band and MetAids band users coexist intensely simultaneously. In this method, threshold power according to the [1] is pulled down by adding extra distance margin in order to minimize the interference effects to the MICS systems using confidence interval calculations. Because received signal strength just below the monitoring threshold power according to the [1] brings about much more interferences for the MICS systems even if listen-before-talk technique is applied.

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A wireless system for gastric slow wave acquisition and gastric electrical stimulation

Cited by 5 publications

References 7 publications

A Miniature Configurable Wireless System for Recording Gastric Electrophysiological Activity and Delivering High-Energy Electrical Stimulation

A Miniature Configurable Wireless System for Recording Gastric Electrophysiological Activity and Delivering High-Energy Electrical Stimulation

Translation of an existing implantable cardiac monitoring device for measurement of gastric electrical slow‐wave activity

Determining Threshold Distance Providing Less Interference for Wireless Medical Implant Communication Systems in Coexisting Environments under Shadow Fading Conditions

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