A web‐based tutorial improves practicing pathologists' Gleason grading of images of prostate carcinoma specimens obtained by needle biopsy

Kronz, Joseph D.; Silberman, Mark A.; Allsbrook, William C.; Epstein, Jonathan I.

doi:10.1002/1097-0142(20001015)89:8<1818::aid-cncr23>3.3.co;2-a

Cited by 8 publications

(7 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, in addition to individual grading performances it is also important to strive for a common grading culture. Some efforts have been made to utilise images for the training of the pathology community in prostate cancer grading although, prior to this study, a platform for international standardisation has not been developed …”

Section: Discussionmentioning

confidence: 99%

Utility of Pathology Imagebase for standardisation of prostate cancer grading

et al. 2018

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Utility of Pathology Imagebase for standardisation of prostate cancer grading

et al. 2018

View full text Add to dashboard Cite

show abstract

“…In a study of interobserver variation for Gleason grading between Japan and the United States, 10 images from needle biopsies of prostatic carcinoma were placed on a CD‐ROM, and similar moderate κ levels were reported to the present study. Two papers have been reported on the use of web‐based tutorial for Gleason grading used by practising pathologists 11 and pathology residents, 12 with positive effects.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the use of digital images for a national prostate core external quality assurance scheme

et al. 2011

View full text Add to dashboard Cite

show abstract

“…Several web sites and CDs provided with textbooks use static digital images to illustrate prostate pathology . A small number of studies have supported the clinical effectiveness of WSIs in situations in which static digital imaging have been shown to be useful, using the ability of WSI/VM to permit navigation across the specimen and examination at multiple magnifications to improve the educational value of the images.…”

Section: Wsi/vm In Prostate Pathologymentioning

confidence: 99%

Utility of whole slide imaging and virtual microscopy in prostate pathology

Camparo¹,

Egevad

Algaba

et al. 2012

APMIS

View full text Add to dashboard Cite

M. Utility of whole slide imaging and virtual microscopy in prostate pathology. APMIS 2012; 120: 298-304.Whole slide imaging (WSI) has been used in conjunction with virtual microscopy (VM) for training or proficiency testing purposes, multicentre research, remote frozen section diagnosis and to seek specialist second opinion in a number of organ systems. The feasibility of using WSI/VM for routine surgical pathology reporting has also been explored. In this review, we discuss the utility and limitations of WSI/VM technology in the histological assessment of specimens from the prostate. Features of WSI/VM that are particularly well suited to assessment of prostate pathology include the ability to examine images at different magnifications as well as to view histology and immunohistochemistry side-by-side on the screen. Use of WSI/VM would also solve the difficulty in obtaining multiple identical copies of small lesions in prostate biopsies for teaching and proficiency testing. It would also permit annotation of the virtual slides, and has been used in a study of inter-observer variation of Gleason grading to facilitate precise identification of the foci on which grading decisions had been based. However, the large number of sections examined from each set of prostate biopsies would greatly increase time required for scanning as well as the size of the digital file, and would also be an issue if digital archiving of prostate biopsies is contemplated. Z-scanning of glass slides, a process that increases scanning time and file size would be required to permit focusing a virtual slide up and down to assess subtle nuclear features such as nucleolar prominence. The common use of large blocks to process prostatectomy specimens would also be an issue, as few currently available scanners can scan such blocks. A major component of proficiency testing of prostate biopsy assessment involves screening of the cores to detect small atypical foci. However, screening virtual slides of wavy fragmented prostate cores using a computer mouse aided by an overview image is very different from screening glass slides using a microscope stage. Hence, it may be more appropriate in this setting to mark the lesional area and focus only on the interpretation component of competency testing. Other issues limiting the use of digital pathology in prostate pathology include the cost of high quality slide scanners for WSI and high resolution monitors for VM as well as the requirement for fast Internet connection as even a subtle delay in presentation of images on the screen may be very disturbing for a pathologist used to the rapid viewing of glass slides under a microscope. However, these problems are likely to be overcome by technological advances in the future.

show abstract

A web‐based tutorial improves practicing pathologists' Gleason grading of images of prostate carcinoma specimens obtained by needle biopsy

Cited by 8 publications

References 0 publications

Utility of Pathology Imagebase for standardisation of prostate cancer grading

Utility of Pathology Imagebase for standardisation of prostate cancer grading

Evaluation of the use of digital images for a national prostate core external quality assurance scheme

Utility of whole slide imaging and virtual microscopy in prostate pathology

Contact Info

Product

Resources

About