A wearable microfluidic device for rapid detection of HIV-1 DNA using recombinase polymerase amplification

Kong, Mengqi; Li, Zihan; Wu, Jianguo; Hu, Jie; Sheng, Ye-Feng; Wu, Di; Lin, Yong; Li, Ming; Wang, Xiaozhi; Wang, Shuqi

doi:10.1016/j.talanta.2019.120155

Cited by 70 publications

(61 citation statements)

References 36 publications

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“…Portable fluorescence detection can be realized in a variety of setups. Among them, low-cost fluorescence detection can be achieved by employing inexpensive UV light 212 (US $2) or LEDs 213 as the excitation sources and relying on naked-eye visualization. Though in practice, a portable imaging device such as a digital camera 212 or a smartphone 213 based STI POCT technologies.…”

Section: Explore Detection Modalitymentioning

confidence: 99%

Bridging the gap between development of point-of-care nucleic acid testing and patient care for sexually transmitted infections

et al. 2022

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Section: Explore Detection Modalitymentioning

confidence: 99%

Bridging the gap between development of point-of-care nucleic acid testing and patient care for sexually transmitted infections

et al. 2022

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“…In other words, the movement of solutions by convection physically transports reagents between reaction zones. Renewable energy sources such as solar and body generated thermal heating can also be used [81,82]. Selfcontained platforms have been reported for smartphone devices that perform both temperature tuneable and timeresolved fluorescence measurements with continuous photographic and self-controlled timing of the detector [83,84].…”

Section: A Smartphone Based Nucleic Acid Testsmentioning

confidence: 99%

A Cross-Disciplinary View of Testing and Bioinformatic Analysis of SARS-CoV-2 and Other Human Respiratory Viruses in Pandemic Settings

Hossain¹,

Brito-Rodriguez

Sedger

et al. 2021

IEEE Access

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The SARS-Coronavirus-2 (SARS-CoV-2) infectious disease, COVID-19, has spread rapidly, resulting in a global pandemic with significant mortality. The combination of early diagnosis via rapid screening, contact tracing, social distancing and quarantine has helped to control the pandemic. The absence of real time response and diagnosis is a crucial technology shortfall and is a key reason why current contact tracing methods are inadequate to control spread. In contrast, current information technology combined with a new generation of near-real time tests offers consumer-engaged smartphone-based "lab-in-a-phone" internet-of-things (IoT) connected devices that provide increased pandemic monitoring. This review brings together key aspects required to create an entire global diagnostic ecosystem. Cross-disciplinary understanding and integration of both mechanisms and technologies for effective detection, incidence mapping and disease containment in near real-time is summarized. Available measures to monitor and/or sterilize surfaces, next-generation laboratory and smartphone-based diagnostic approaches can be brought together and networked for instant global monitoring that informs Public Health policy. Cloud-based analysis enabling real-time mapping will enable future pandemic control, drive the suppression and elimination of disease spread, saving millions of lives globally. A new paradigm is introducedscaled and multiple diagnostics for mapping and spreading of a pandemic rather than traditional accumulation of individual measurements. This can do away with the need for ultra-precise and ultra-accurate analysis by taking mass measurements that can relax tolerances and build resilience through networked analytics and informatics, the basis for novel swarm diagnostics. These include addressing ethical standards, local, national and international collaborative engagement, multidisciplinary and analytical measurements and standards, and data handling and storage protocols.

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“…Convection movement of solutions is the driving force that physically transports reagents between the reaction zones. Other variations use renewable energy sources such as solar heat radiations to actuate the reactions [76,77]. A self-contained platform has been reported that explores capability for a smartphone device that performs both temperature tuneable and time-resolved fluorescence measurements with continuous photographic and self-controlled timing of the detector [78,79].…”

Section: Smartphone Based Rapid Diagnosticsmentioning

confidence: 99%

Network Diagnostics for Rapid Testing, Mapping and Bioinformatics Analysis of SARS-CoV-2 and Other Human Respiratory Viruses in Pandemic Settings

Hossain¹

2021

Preprint

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A wearable microfluidic device for rapid detection of HIV-1 DNA using recombinase polymerase amplification

Cited by 70 publications

References 36 publications

Bridging the gap between development of point-of-care nucleic acid testing and patient care for sexually transmitted infections

Bridging the gap between development of point-of-care nucleic acid testing and patient care for sexually transmitted infections

A Cross-Disciplinary View of Testing and Bioinformatic Analysis of SARS-CoV-2 and Other Human Respiratory Viruses in Pandemic Settings

Network Diagnostics for Rapid Testing, Mapping and Bioinformatics Analysis of SARS-CoV-2 and Other Human Respiratory Viruses in Pandemic Settings

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