A water-soluble Fe3+ selective fluorescent turn-on chemosensor: Preparation, theoretical study and its optical vitro imaging

Wang, Lei; Li, Wenxuan; Zhi, Wenjing; Wang, Yun; Han, Juan; Cao, Zhengyang; Ni, Liang; Li, Haoran; Jing, Junjie

doi:10.1016/j.jlumin.2017.12.061

Cited by 20 publications

(5 citation statements)

References 25 publications

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“…The probe 32 has been applied to detect basal level Fe 3+ and the dynamic changes in Fe 3+ levels in live bovine aortic endothelial cells (BAEC) at a subcellular resolution that reveal two Fe 3+ pools in endosomes/lysosomes and mitochondria. The probe 33 forms complex with Fe 3+ in 2:1 binding ratio and shows significant fluorescence enhancement at 588 nm [41]. The probes detect Fe 3+ better in the basic condition (pH 7 to 10), and the estimated LOD is 92 nM.…”

Section: Fluorescent Turn-on Probes For Fe(iii)mentioning

confidence: 99%

Recent Advances on Iron(III) Selective Fluorescent Probes with Possible Applications in Bioimaging

Sahoo

Crisponi

2019

Molecules

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Iron(III) is well-known to play a vital role in a variety of metabolic processes in almost all living systems, including the human body. However, the excess or deficiency of Fe3+ from the normal permissible limit can cause serious health problems. Therefore, novel analytical methods are developed for the simple, direct, and cost-effective monitoring of Fe3+ concentration in various environmental and biological samples. Because of the high selectivity and sensitivity, fast response time, and simplicity, the fluorescent-based molecular probes have been developed extensively in the past few decades to detect Fe3+. This review was narrated to summarize the Fe3+-selective fluorescent probes that show fluorescence enhancement (turn-on) and ratiometric response. The Fe3+ sensing ability, mechanisms along with the analytical novelties of recently reported 77 fluorescent probes are discussed.

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Section: Fluorescent Turn-on Probes For Fe(iii)mentioning

confidence: 99%

Recent Advances on Iron(III) Selective Fluorescent Probes with Possible Applications in Bioimaging

Sahoo

Crisponi

2019

Molecules

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“…During biological processes, Fe 3+ is an important metal ion that involving oxygen uptake, oxygen metabolism and electronic transfer. The lack of Fe 3+ can induce many serious diseases in humans, including anemia, decline of immunity and virus infection [41]. Hence, it is important to investigate the biocompatibility behavior of the prepared BRF in vitro.…”

Section: Resultsmentioning

confidence: 99%

Isolation of the Flavonoid from Bamboo Residues and Its Application as Metal Ion Sensor in Vitro

Dong

et al. 2019

Polymers

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Fluorescence sensors prepared from natural polymers have received increasing attention based on their luminescence characteristics for bioimaging, cell imaging, and intracellular detection of inorganic metabolites. In this work, flavonoids isolated from bamboo residues (BRF) were applied as fluorescence sensors for different metal cations’ detection in vitro. Results showed the optimal flavonoids extraction condition of solid to liquid ratio, ethanol concentration, extraction time and temperature were determined at 1:25, 50%, 240 min and 90 °C, respectively, resulting in an extraction yield with 104.7 mg/100 g bamboo residues. The BRF is mainly composed of isoorientin, isovitexin, pinosylvin, tricin and isorhamnetin by liquid chromatography–mass spectrometry (LC-MS) analysis. It is found that the BRF displayed strong blue-green emission as well as notable excitation, which can selectively and sensitively detect Fe3+ with the limit of detection (LOD) as low as 38.0 nM. In the Fe3+ detection was no obvious interference by other cations except for Al3+. In addition, the BRF displayed excellent biocompatibility that can be applied to bioimages of the intracellular detection of Fe3+ in L02 cells. Finally, it is found that the BRF possessed significant antioxidant properties in scavenging H2O2-induced endogenous reactive oxygen species (ROS) in a zebrafish module (in vivo) and L02 cells (in vitro). These results showed that the flavonoid products sustainably isolated from an abundant lignocellulosic waste appear to be effective fluorescent sensors for Fe3+ detection in biological systems with excellent biocompatibility and antioxidant activity.

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“…It was well known that the sensing responses of most fluorescence sensors were affected by the pH values of the solution . In order to gain the optimum pH value, the fluorescence responses of sensor L1 with and without addition of Fe 3+ ion was recorded with pH values ranging from 2.3‐12.3, as depicted in Figure S1, without Fe 3+ ion, the fluorescence intensity of L1 had no obvious change among the pH range from 2.3 to 12.3.…”

Section: Resultsmentioning

confidence: 99%

“…The hydroxyl group seemed not a necessary group in the sensing of the Fe 3+ ions, as the compared compound L2, which devoid of OH group shown the similar fluorescence response toward the aforementioned ions (Fig.S2‐7). The fluorescence quenching could be ascribed to the paramagnetic quenching effect of Fe 3+ and/or ligand to metal charge transfer (LMCT) …”

Section: Resultsmentioning

confidence: 99%

Fluorescence Sensors for Fe³⁺ Ion with High Selectivity and Sensitivity and Bioimaging in Living Cells

et al. 2018

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Two fluorescence sensors L1 and L2 were designed and synthesized. They exhibited fluorescence emission at 570 nm in DMSO/H2O (Tris buffer, pH=7.4, v/v=5: 1). The sensors L1 and L2 displayed excellent sensitivity specific toward Fe3+ in comparison to other environmentally important metal ions, including Fe2+ ions, and the detection limit was as low as 5.11×10−8 M. Furthermore, living PC‐12 cell imaging experiments indicated that the sensors L1 and L2 were cell‐permeable and they could be used to detect intracellular Fe3+ ions.

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A water-soluble Fe3+ selective fluorescent turn-on chemosensor: Preparation, theoretical study and its optical vitro imaging

Cited by 20 publications

References 25 publications

Recent Advances on Iron(III) Selective Fluorescent Probes with Possible Applications in Bioimaging

Recent Advances on Iron(III) Selective Fluorescent Probes with Possible Applications in Bioimaging

Isolation of the Flavonoid from Bamboo Residues and Its Application as Metal Ion Sensor in Vitro

Fluorescence Sensors for Fe³⁺ Ion with High Selectivity and Sensitivity and Bioimaging in Living Cells

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A water-soluble Fe3+ selective fluorescent turn-on chemosensor: Preparation, theoretical study and its optical vitro imaging

Cited by 20 publications

References 25 publications

Recent Advances on Iron(III) Selective Fluorescent Probes with Possible Applications in Bioimaging

Recent Advances on Iron(III) Selective Fluorescent Probes with Possible Applications in Bioimaging

Isolation of the Flavonoid from Bamboo Residues and Its Application as Metal Ion Sensor in Vitro

Fluorescence Sensors for Fe3+ Ion with High Selectivity and Sensitivity and Bioimaging in Living Cells

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About

Fluorescence Sensors for Fe³⁺ Ion with High Selectivity and Sensitivity and Bioimaging in Living Cells