A Wash-Free Spheres-on-Sphere Strategy for On-Site and Multiplexed Biosensing
Peng Lu,
Chen Zhan,
Chenxi Huang
et al.
Abstract:Respiratory infections and food contaminants pose severe challenges to global health and the economy. A rapid onsite platform for the simultaneous detection of multiple pathogens is crucial for accurate diagnosis, appropriate treatment, and a reduced healthcare burden. Herein, we present a spheres-on-sphere (SOS) platform for multiplexed detection using a portable Coulter counter, which employs millimeter-and micron-sized spheres coupled with antibodies as multitarget probes. The assay allows for quantitative … Show more
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