A View from the past into our collective future: the oncofertility consortium vision statement

Woodruff, Teresa K.; Ataman, Lauren; Acharya, Kelly S.; Almeida‐Santos, Teresa; Anazodo, Antoinette; Anderson, Richard A.; Appiah, Leslie; Bader, Joy; Becktell, Kerri; Brannigan, Robert E.; Breech, Lesley; Bourlon, María Teresa; Bumbulienė, Žana; Burns, Karen; Campo‐Engelstein, Lisa; Campos, Jacira Ribeiro; Centola, Grace M.; Chehin, Maurício B.; Chen, Diane; Vos, M. De; Duncan, Francesca E.; El-Damen, Ahmed; Fair, Douglas; Famuyiwa, Yemi; Fechner, Patricia Y.; Fontoura, Paula; Frias, Olivia; Gerkowicz, Sabrina A.; Ginsberg, Jill P.; Gracia, Clarisa R.; Goldman, Kara N.; Gómez-Lobo, Veronica; Hazelrigg, Brent; Hsieh, Michael H.; Hoyos, Luis R.; Hoyos-Martínez, Alfonso; Jach, Robert; Jassem, Jacek; Javed, Murid; Jayasinghe, Yasmin; Jeelani, Roohi; Jeruss, Jacqueline S.; Kaul-Mahajan, Nalini; Keim‐Malpass, Jessica; Ketterl, Tyler G.; Khrouf, Mohamed; Kimelman, Dana; Kusuhara, Atsuko; Kutteh, William H.; Laronda, Monica M.; Lee, Jung Ryeol; Lehmann, Vicky; Letourneau, Joseph M.; McGinnis, Lynda K.; McMahon, Eileen; Meacham, Lillian R.; Mijangos, Monserrat Fabiola Velez; Moravek, Molly B.; Nahata, Leena; Ogweno, George Moses; Orwig, Kyle E.; Pavone, Mary Ellen; Peccatori, Fedro Alessandro; Pesce, Romina; Pulaski, Hanna; Quinn, Gwendolyn P.; Quintana, R.; Quintana, Tomas; Carvalho, Bruno Ramalho de; Ramsey‐Goldman, Rosalind; Reinecke, Joyce; Reis, Fernando M.; Rios, Julie Sroga; Rhoton‐Vlasak, Alice; Rodriguez‐Wallberg, Kenny A.; Roeca, Cassandra; Rotz, Seth J.; Rowell, Erin E.; Salama, Mahmoud; Saraf, Amanda; Scarella, Aníbal; Schafer-Kalkhoff, Tara; Schmidt, Deb; Senapati, Suneeta; Shah, Divya; Shikanov, Ariella; Shnorhavorian, Margarett; Skiles, Jodi; Smith, James F.; Smith, Kristin; Sobral, Fabio; Stimpert, Kyle; Su, H. Irene; Sugimoto, Kouhei; Suzuki, Nao; Thakur, Mili; Victorson, David; Viale, Luz; Vitek, Wendy; Wallace, W. Hamish B.; Wartella, Ellen; Westphal, Lynn M.; Whiteside, Stacy; Wilcox, Lea H; Wyns, Christine; Xiao, Shuo; Xu, Jing; Zelinski, Mary B.

doi:10.1007/s10815-020-01983-4

Cited by 28 publications

(15 citation statements)

References 74 publications

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“…It is in this setting that oncofertility is working to provide information about the iatrogenic effects of drugs on reproductive organs and to develop strategies that will preserve and restore reproductive function and health for cancer survivors. Addressing the complex treatment plans and general health and quality of life concerns of young cancer patients whose fertility may be threatened by their disease or its treatment is a priority, and the Oncofertility Consortium has formally led efforts in this area since 2006 [ 1 , 6 – 21 ].…”

Section: Introductionmentioning

confidence: 99%

“…Since its founding, the Oncofertility Consortium not only pioneers the science in the field, but also convenes the leaders and learners in the field annually at the Oncofertility Conference, which showcases groundbreaking research and creating momentum for future activities and initiatives (Table 1 ) [ 16 , 21 , 22 ]. Each year, the meeting brings together scientists, researchers, clinicians, and others in the fields of reproduction, to discuss contemporary oncofertility and fertility preservation issues, including recent advances in reproductive health for all patients receiving gonadotoxic treatment.…”

Section: Introductionmentioning

confidence: 99%

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A synopsis of global frontiers in fertility preservation

Ataman

Laronda

Gowett

et al. 2022

J Assist Reprod Genet

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Since 2007, the Oncofertility Consortium Annual Conference has brought together a diverse network of individuals from a wide range of backgrounds and professional levels to disseminate emerging basic and clinical research findings in fertility preservation. This network also developed enduring educational materials to accelerate the pace and quality of field-wide scientific communication. Between 2007 and 2019, the Oncofertility Consortium Annual Conference was held as an in-person event in Chicago, IL. The conference attracted approximately 250 attendees each year representing 20 countries around the world. In 2020, however, the COVID-19 pandemic disrupted this paradigm and precluded an in-person meeting. Nevertheless, there remained an undeniable demand for the oncofertility community to convene. To maintain the momentum of the field, the Oncofertility Consortium hosted a day-long virtual meeting on March 5, 2021, with the theme of “Oncofertility Around the Globe” to highlight the diversity of clinical care and translational research that is ongoing around the world in this discipline. This virtual meeting was hosted using the vFairs ® conference platform and allowed over 700 people to participate, many of whom were first-time conference attendees. The agenda featured concurrent sessions from presenters in six continents which provided attendees a complete overview of the field and furthered our mission to create a global community of oncofertility practice. This paper provides a synopsis of talks delivered at this event and highlights the new advances and frontiers in the fields of oncofertility and fertility preservation around the globe from clinical practice and patient-centered efforts to translational research. Supplementary Information The online version contains supplementary material available at 10.1007/s10815-022-02570-5.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A synopsis of global frontiers in fertility preservation

Ataman

Laronda

Gowett

et al. 2022

J Assist Reprod Genet

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“…Despite challenges, many opportunities exist to improve oncofertility practice in limited resource settings and create potential for the future including improved cancer survival rates and improved success rates of several oncofertility options as well as emergence of new promising technologies. The Oncofertility Consortium will continue to engage more stakeholders from the USA and abroad to help build a sustainable oncofertility core competency worldwide according to the Oncofertility Consortium Vision 2030 [ 52 ].…”

Section: Discussionmentioning

confidence: 99%

Installing oncofertility programs for breast cancer in limited versus optimum resource settings: Empirical data from 39 surveyed centers in Repro-Can-OPEN Study Part I & II

Salama

Lambertini

Christianson

et al. 2022

J Assist Reprod Genet

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Purpose As a further step to elucidate the actual diverse spectrum of oncofertility practices for breast cancer around the globe, we present and discuss the comparisons of oncofertility practices for breast cancer in limited versus optimum resource settings based on data collected in the Repro-Can-OPEN Study Part I & II. Methods We surveyed 39 oncofertility centers including 14 in limited resource settings from Africa, Asia & Latin America (Repro-Can-OPEN Study Part I), and 25 in optimum resource settings from the United States, Europe, Australia and Japan (Repro-Can-OPEN Study Part II). Survey questions covered the availability of fertility preservation and restoration options offered to young female patients with breast cancer as well as the degree of utilization. Results In the Repro-Can-OPEN Study Part I & II, responses for breast cancer and calculated oncofertility scores showed the following characteristics: (1) higher oncofertility scores in optimum resource settings than in limited resource settings especially for established options, (2) frequent utilization of egg freezing, embryo freezing, ovarian tissue freezing, GnRH analogs, and fractionation of chemo- and radiotherapy, (3) promising utilization of oocyte in vitro maturation (IVM), (4) rare utilization of neoadjuvant cytoprotective pharmacotherapy, artificial ovary, and stem cells reproductive technology as they are still in preclinical or early clinical research settings, (5) recognition that technical and ethical concerns should be considered when offering advanced and innovative oncofertility options. Conclusions We presented a plausible oncofertility best practice model to guide oncofertility teams in optimizing care for breast cancer patients in various resource settings.

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“…Over the past 20 years, addressing future fertility has become a critical component of care for reproductiveaged men and women with new cancer diagnoses. 1 With the expansion of carrier screening for deleterious germline mutations, it is crucial to address the significant implications carrier status has for future fertility and promote early intervention for fertility preservation. However, significant gaps exist in both physician and patient knowledge regarding reproductive options and potential benefits for reproductive-aged men and women who are carriers of deleterious BRCA mutations.…”

Section: Introductionmentioning

confidence: 99%