A verification of correlation between chemical monitoring and multi-biomarker approach using clam Ruditapes philippinarum and scallop Chlamys farreri to assess the impact of pollution in Shandong coastal area of China

Tetrabromobisphenol A acts a neurodevelopmental disruptor in early larval stages of Mytilus galloprovincialis

“…TBBPA final concentrations (1 and 10 µg/L, corresponding to 1.8 and 18 nM, respectively), depending on the endpoint measured, were chosen among those encompassing higher levels detected in polluted coastal areas (Gong et al, 2017;Li et al, 2020), as well as the EC50 values previously obtained for TBBPA in the 48 h embryotoxicity assay (Fabbri et al, 2014). Higher, embryotoxic concentrations (100 µg/L) were also utilized to confirm the effects on shell formation at early stages.…”

“…Levels of TBBPA in urbanized coastal areas range from ng to µg in both sediments (g −1 dw) and waters (L -1 ) (Liu et al, 2016;Sühring et al, 2015;Gong et al, 2017 and refs therein). High concentrations (>1 µg L -1 ) detected at polluted sites (Liu et al, 2016;Gong et al, 2017;Li et al, 2020) are comparable to TBBPA levels in urban soils and freshwater, suggesting that coastal seawater may receive discharge from industrial effluents or landfill leakages without effective treatment.…”

“…In this work, the effects and mechanisms of action of TBBPA were further investigated in mussel larvae at different times post fertilization, with special emphasis on early shell formation, the key step in the transition from the trocophora (24 hpf) to the first D-veliger stage (48 hpf), as well as on neurodevelopment. Concentrations were chosen among those encompassing the EC50 values obtained in the 48 h larval developmental assay (1 and 10 µg/L, depending on the endpoint measured) (Fabbri et al, 2014), and environmental levels detected in polluted coastal areas (Liu et al, 2016, Gong et al, 2017Li et al, 2020). Higher, embryotoxic concentrations (100 µg/L) (Fabbri et al, 2014) were also utilized to evaluate the effects on shell formation at earlier stages.…”

Application of hyperspectral imaging technology for rapid identification of Ruditapes philippinarum contaminated by heavy metals

“…1 Heavy metals such as copper (Cu), lead (Pb), cadmium (Cd), and zinc (Zn) contaminate the aquatic environment and pollute aquatic products. 2 With rapid accumulation of high concentrations of heavy metals, it poses a hazard to human health. 3 At present, standard methods to detect heavy metals include ame atomic absorption spectrometry, graphite furnace atomic absorption spectrometry, and atomic uorescence spectrometry, 4,5 which can precisely measure the types and concentrations of the heavy metals.…”

“… 1 Heavy metals such as copper (Cu), lead (Pb), cadmium (Cd), and zinc (Zn) contaminate the aquatic environment and pollute aquatic products. 2 With rapid accumulation of high concentrations of heavy metals, it poses a hazard to human health. 3 …”