A variant form of Laurin–Sandrow syndrome in an adult patient

Buzea, Cezar; Panazan, Teodor; Boiangiu, Ileana

doi:10.1177/1753193419892560

Cited by 2 publications

(1 citation statement)

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“…Martinez-Frias (1994) reported the 7th case and suggested that the triad of mirror hand, mirror feet and nasal anomalies form the Laurin-Sandrow syndrome. Afterward several cases, but not identical have been reported: Hersch et al ., (1995) one case, Hatchwell and Dennis (1996) two cases, Pilkington et al ., (2000) one case, Kantaputra (2001) one case, Lohan et al ., (2004) four cases, Innis and Hedera (2004) two cases, Kjaer et al ., (2005) two cases, Marino-Enriquez et al .,(2008) one case, Patil and Bhat (2013) one case, Salinas-Torres (2014) two cases, Roman and Lypka (2017) three cases and Buzea et al ., (2020) one case. In total, 28 cases have been reported, 25 cases being extensively described in the articles above mentioned.…”

Section: Introductionmentioning

confidence: 97%

“Laurin-Sandrow Syndrome – a review of the literature and classification system”

Buzea

Boulanger

2022

Clinical Dysmorphology

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Introduction Laurin-Sandrow syndrome also known as tetramelic mirror-image polydactyly is a rare congenital disorder characterized classically by polysyndactyly of the hands, mirror feet and nose anomalies (hypoplasia of the nasal alae and short columella) often associated with ulnar and/or fibular duplication. As a pathologic entity, it is heterogeneous, the patients displaying a variety of symptoms. This review aims to analyze the different aspects of the condition, such as clinical findings and methods of treatment to summarize the principal features of Laurin-Sandrow syndrome. Materials and methodsThe review is based on searches on PubMed, Web of Science and Researchgate of the following terms: "Laurin-Sandrow syndrome", "mirror hands", "mirror feet", "tetramelic mirror-image polydactyly", "fibular dimelia" and "ulnar dimelia". Clinical cases, reviews and original articles were included. ResultsAs a consequence of our findings, we suggest a modification of the Al-Qattan classification system for Mirror Hand-Multiple Hand Spectrum. ConclusionEven though it has an extremely low incidence, a thorough understanding of the syndrome enables the surgeon to choose the appropriate treatment with the ultimate goal to improve the patient's life quality.

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