The manuscript analyzes the stimulation for an Enhanced Geothermal System development in Acoculco, Mexico. Using an analytical penny-shaped hydraulic fracture model covering different propagation regimes, we computed the final fracture length and width by varying fluid properties with temperature. Our analysis indicates that for the given scenario, the fluid viscosity plays a minor role and instead flow rate and time of the stimulation are the controlling variables. We computed the fracture reopening as a consequence of water reinjection in the second stage of the stimulation through numerical computations based on the enriched discontinuity method. The computation shows that a single isolated fracture will not provide sufficient permeability, as the continuous injection will quickly fill and pressurize the crack. We demonstrate that the fracture needs to be connected to a permeable network to avoid excessive pressurization and achieve a commercially exploitable reservoir for Enhanced Geothermal System. Plain Language Summary At Acoculco, Mexico, the temperature of the rock at 2 km depth is approximately 300°C, which can be potentially exploited for the production of geothermal energy. To produce deep geothermal energy, water must be extracted from the rock, which is currently not possible in Acoculco because the host rock, a granite, is practically impermeable. A possible solution is to inject water into the rock formation and create one or multiple large fractures: Through the fractures, the fluid will be able to circulate and geothermal energy can be extracted. In this work, we show, through numerical calculations, that it will be relatively easy to create a large fracture by injecting high-pressure fluid, but if the fracture is not connected to a network of preexisting fractures, harvesting geothermal energy would be unlikely. The pressure will rapidly increase during the reinjection, which could trigger induced earthquakes if it exceeds sufficiently large values. We suggest instead to create fractures in multistage and maximize a chance of intersecting existing networks through zonal isolation.