Abstract:Metformin is oral hypoglycemic or blood sugar-lowering drug which is used for the first-line drug in the treatment of diabetes mellitus type 2. This study presented the validated of Ultra Performance Liquid Chromatography UltraViolet (UPLC-UV) method for the determination of metformin in human plasma. Metformin levels were measured using UPLC with UV detector and liquid-liquid extraction method. Separation was carried out on a Acquity UPLC HSS T3 100mm × 2.1mm i.d. column (1.8μm partikel size) using gradient e… Show more
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