A validated tool to predict colorectal neoplasia and inform screening choice for asymptomatic subjects

Abstract

The scoring system based on age, gender, smoking, family history, Body Mass Index and self-reported diabetes is useful in predicting the risk of colorectal neoplasia.

Risk prediction models for colorectal cancer: A Scoping review

“…A majority (n=35) of models include variables obtained through a questionnaire [18,19,21,22,23,24,25,26,27,28,30,33,36,37,38,39,40,41,42,43,44,45,46,49,50,51,53,54]. The questionnaires range from those with only one or two simple questions to those with detailed questions on factors such as diet, physical activity, alcohol and smoking habits and past medical facts.…”

“…A majority of the studies have used multiple logistic regression to identify the risk predictors [16,27,28,30,33,34,35,41,43,47,50,52] followed by the allocation of the risk points, based on the values of beta-coefficients [14,15,18,21,23,24,36,37,39,45,46,48]. Fourteen models have incorporated Cox proportional hazards regression to develop the risk model and the score [17,19,20,22,38,40].…”

“…Three models have been developed in China [16,23,36] and Japan [40] while, Netherlands [25,26], Germany [21], Taiwan [32,46] and United Kingdom [31,34] have developed two models each. Many other countries, such as Australia [19], Poland [24], Hong Kong [28], Italy [29], Qatar [41], Saudi Arabia [43], Spain [52] and Sri Lanka [15] have also developed country-specific risk prediction models for colorectal cancer. When considering the global approach two models have been developed globally [27,30] while another has been developed for Asia [37].…”

Colorectal Cancer Screening Based on Age and Gender: A Cost-effectiveness Analysis

“…More details could be found elsewhere. [19][20][21] We assumed the rate of compliance with colonoscopy was 98.9%. The overall age-adjusted rate of polypectomy was 43.5% (50.3% for male and 37.3% for female), cumulative over 20 years when the screening participants join the program at 50 years till 70-year old.…”

Challenges to the adoption of risk algorithms for colorectal cancer screening programmes: perspectives for future research

“…6 Other validated risk scores have been constructed using similar methods and have potential for use in clinical practice. 7,8 Yeoh et al 5 also identified some issues related to the application of the APCS score. The objective of this commentary is to discuss the potential challenges and perspectives for future research into risk-based CRC screening.…”