A validate and standardized pseudotyped microneutralization assay as a safe and powerful tool to measure LASSA neutralising antibodies for vaccine development and comparison
Roberta Antonelli,
Vittoria Forconi,
Eleonora Molesti
et al.
Abstract:Background Over the past few decades, WHO has made massive efforts to promote the development of a vaccine against Lassa virus (LASV), one of the top ten priority pathogens for research and development under the WHO R&D Blueprint for Emerging Infections. To date, several vaccines are at different stages of development. In this scenario, a validated and standardised assay to measure LSV neutralising antibodies is urgently needed for vaccine development and comparison. Methods The neutralisation assay remain… Show more
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