A Useful Route to Metal Complexes of Poorly Coordinating Sulfonamides

Abstract

We report a synthetic approach towards metal complexes of the poorly coordinating sulfonamide 2-tosylaminomethylaniline (HL Ts ) that exploits both the good donor capacity of imine N atoms and the hydrolysis of imine ligands mediated by d-block metals. Zn 2+ , Cd 2+ and Pd 2+ ions appear to pro-

Stimulation of Sulfonamides Antibacterial Drugs Activity as a Result of Complexation with Ru(III): Physicochemical and Biological Study

“…The results of ESI-MS analysis of each of the Ru(III) complexes containing sulfonamide derivatives supported the proposed structure of the coordination compounds. Moreover, the experimental data obtained for all the studied Ru(III) compounds are in good agreement with and correspond well to a previous report on a similar type of complexes [47].…”

“…The data provided refer to the two absorption bands at 204 and 261 nm obtained with highly diluted solutions of (1) and (2). These bands corresponded to π-π* transitions attributed to the aromatic rings [47] of the sulfonamide ligands. The spectra registered for both complexes in the visible region were dominated by the expected d-π* MLCT transitions (435 and 517 nm for compound (1); 532 nm for compound (2)).…”

Controlling ring-chain tautomerism through steric hindrance

“…12,13 With regard to the aldehyde residue, the short length of the O3-H3/N2 interaction (2.56Å) provides evidence of its intensity, allowing its qualication as strong intramolecular resonance-assisted H-bond (RAHB). 12,13 With regard to the aldehyde residue, the short length of the O3-H3/N2 interaction (2.56Å) provides evidence of its intensity, allowing its qualication as strong intramolecular resonance-assisted H-bond (RAHB).…”

“…5). 12,13,23 Since the N4-H/N1 distance is about 2.89Å and NHN angle is less than 130 , the intramolecular H bond is not very signicant. An attempt of crystallising the chain tautomer in chloroform led to crystals of rac-H 2 L 2 TQ $HCCl 3 (Fig.…”

“…12,13 Thus, reaction times of about 1 h gave the open-chain tautomer as the main product, however, as time goes on, the ring-chain ratio is increasing, and aer several hours the ring tautomer is clearly the most abundant product in the brute. 12,13 Thus, reaction times of about 1 h gave the open-chain tautomer as the main product, however, as time goes on, the ring-chain ratio is increasing, and aer several hours the ring tautomer is clearly the most abundant product in the brute.…”