A universe of human gut-derived bacterial prophages: unveiling the hidden viral players in intestinal microecology
Zhangming Pei,
Yufei Liu,
Yutao Chen
et al.
Abstract:Prophages, which are an existing form of temperate phages that integrate into host genomes, have been found extensively present in diverse bacterial species. The human gut microbiome, characterized by its complexity, dynamism, and interconnectivity among multiple species, remains inadequately understood in terms of the global landscape of bacterial prophages. Here, we analyzed 43,942 human gut-derived bacterial genomes (439 species of 12 phyla) and identified 105,613 prophage regions in ~ 92% of them. 16254 co… Show more
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