A universal electrochemical biosensor based on CRISPR/Cas12a and a DNA tetrahedron for ultrasensitive nucleic acid detection

Dong, Jiangbo; Li, Xinyao; Hu, Wenxi; Liu, Meilin; Hou, Changjun; Hou, Jingzhou; Yang, Mei; Huo, Danqun

doi:10.1039/d4cc01646g

Chem. Commun.

2024

DOI: 10.1039/d4cc01646g

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A universal electrochemical biosensor based on CRISPR/Cas12a and a DNA tetrahedron for ultrasensitive nucleic acid detection

Jiangbo Dong,

Xinyao Li,

Wenxi Hu

et al.

Abstract: Herein, a universal nucleic acid analysis platform was constructed for sensitive and accurate detection of miRNA-155 and ctDNA using isothermal amplification-assisted CRISPR/Cas12a and DNA tetrahedral nanostructures (TDN) supported sensing interface....

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A universal electrochemical biosensor based on CRISPR/Cas12a and a DNA tetrahedron for ultrasensitive nucleic acid detection

Abstract: Herein, a universal nucleic acid analysis platform was constructed for sensitive and accurate detection of miRNA-155 and ctDNA using isothermal amplification-assisted CRISPR/Cas12a and DNA tetrahedral nanostructures (TDN) supported sensing interface....

Cited by 0 publications

References 20 publications

No citations

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