A Unique Cause of Pulmonary Hemorrhage: A Case of Atypical Hemolytic Uremic Syndrome in a Patient With Antiphospholipid Antibody Syndrome

Yousuf, Saad; Junaid, Nida; Adeboye, Adedamola; Nazir, Habib; Scatliffe, Kristen; Patel, Pratik; Cohen, Alice

doi:10.1016/j.chest.2017.08.924

Cited by 2 publications

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“…APL are a series of autoimmune antibodies, the existence of which is related to thrombosis and recurrent abortion [ 22 ]. Regardless of the titer of anticardiolipin antibody, anticardiolipin antibody can bind to phospholipids on plasma proteins, such as prothrombin, β -2GPI, and V-annexin, and become a risk factor for thrombosis in patients with systemic lupus erythematosus or recurrent abortion [ 23 ]. These antibodies are more common and have higher titers in patients with primary APS and systemic lupus erythematosus than in patients with recurrent abortion.…”

Section: Discussionmentioning

confidence: 99%

“…These antibodies are more common and have higher titers in patients with primary APS and systemic lupus erythematosus than in patients with recurrent abortion. APL IgG or IgM, anti- β 2GPI antibodies, anti-PT antibodies, and anti-V annexin antibodies accounted for 100%, 80%, 60%, and 24% of primary APS patients, respectively, compared with 66% of recurrent abortion patients whose above antibodies were negative, of which ACL IgG or IgM, anti- β 2GPI antibodies, anti-PT antibodies, and anti-V annexin antibodies accounted for 6%, 6%, 16%, and 17%, respectively [ 23 ]. Thrombosis and thrombocytopenia are common in patients with SLE and primary APS, but rare in patients with recurrent abortion.…”

Section: Discussionmentioning

confidence: 99%

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Effects of Comprehensive Nursing Based on Orem’s Self-Care Theory on Symptom Improvement and Pregnancy Outcome in Patients with Antiphospholipid Syndrome: A Retrospective Cohort Study

Meng

Bai

2022

Computational and Mathematical Methods in Medicine

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Objective. A retrospective cohort study was conducted to explore the effects of comprehensive nursing based on Orem’s self-care theory on symptom improvement and pregnancy outcomes in patients with antiphospholipid syndrome (APS). Methods. Sixty patients with antiphospholipid antibody syndrome treated in our hospital from February 2019 to April 2021 were enrolled. The control group received comprehensive nursing, while the study group received comprehensive nursing based on Orem’s self-care theory. Nursing satisfaction, self-nursing ability, anxiety score, social support status, pregnancy outcome, and the score of life quality were compared between the two groups. Results. First of all, we compared the nursing satisfaction, the study group was very satisfied in 23 cases, satisfactory in 5 cases, general in 2 cases, the satisfaction rate was 100.00%. While in the control group, 11 cases were very satisfied, 10 cases were satisfied, 4 cases were general, and 5 cases were dissatisfied, the satisfaction rate was 83.33%. The nursing satisfaction in the study group was higher compared to the control group ( P < 0.05 ). Secondly, the self-concept, sense of self-care responsibility, self-nursing skills, health knowledge, and total score of the study group were higher compared to the control group ( P < 0.05 ). After intervention, the anxiety scores of the two groups decreased. Compared between the two groups, the anxiety scores of the study group before intervention and 1 week, 2 weeks, 3 weeks, and 4 weeks after intervention were lower compared to the control group ( P < 0.05 ). The comparison of social support showed that the scores of objective support, subjective support, utilization of support, and total score of social support in the study group were higher compared to the control group ( P < 0.05 ). The number of abortions in the control group was lower compared to the control group, and the number of full-term deliveries was higher compared to the control group ( P < 0.05 ). Finally, we compared the scores of life quality. After nursing, the scores of life quality of the two groups increased. Of note, the scores of physiological function, psychological function, social function, and health self-cognition in the study group were lower compared to the control group ( P < 0.05 ). Conclusion. Comprehensive nursing for patients with APS based on Orem’s self-care theory can effectively improve clinical symptoms and pregnancy outcome and play a positive role in facilitating patients’ nursing satisfaction and self-nursing ability, which can also effectively strengthen mental health and social support, this nursing model is worth popularizing in clinic.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%