A unique case of keratoconus with Cogan-Reese syndrome and secondary glaucoma

Chakrabarty, Lipi

doi:10.4103/ijo.ijo_986_15

Cited by 5 publications

(6 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Another demographic observation noted was that KC had a late onset, at age 30, similar to the other case reports. [6][7][8][9] Although KC commonly appears in the teens and progresses more rapidly in younger patients, there is a possibility of late onset and progression even later in life. Thus, it is prudent to follow-up these cases for a longer term than primary KC.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Corneal Collagen Cross-Linking for Late Onset Progressive Keratoconus in Iridocorneal Endothelial Syndrome

Phylactou

Din

Aiello

et al. 2023

Cornea

View full text Add to dashboard Cite

The aim of this study was to report the first case of successful use of corneal collagen cross-linking (CXL) to halt the progression of keratoconus in a patient with concurrent iridocorneal endothelial (ICE) syndrome.Methods: A 30-year-old White man was referred to our subspecialty corneal clinic for further investigation of right corectopia. The patient was asymptomatic and was otherwise fit. Slit-lamp examination revealed a right oval-shaped pupil decentered superiorly, a transillumination defect at the 5-o'clock position, minimal gutta-like changes in the corneal endothelium, and few inferior peripheral anterior synechiae. Dilated fundoscopy was normal in both eyes, with healthy optic discs, maculae, and peripheral retinae. Specular microscopy and slit-lamp findings suggested ICE syndrome. Subsequent investigation with corneal tomography showed progressive signs of inferior corneal ectasia with steepening, and thinning in the right eye, consistent with keratoconus. The left eye was unremarkable.Results: Epithelium-off accelerated corneal CXL was performed in the affected eye. Early post-CXL follow-up (1 week) was unremarkable, and further follow-ups were arranged at 3, 6, 12, and 24 months, respectively. In subsequent reviews, the patient's vision and corneal tomography findings were stable. Conclusions:We describe the first case of corneal CXL for progressive keratoconus with ICE syndrome. co-existing keratoconus and ICE syndrome can occur, and corneal cross-linking was used successfully in this case to halt keratoconus progression. However, further studies will need to establish the impact of epithelium-off corneal cross-linking, especially in more severely affected eyes.

show abstract

Section: Discussionmentioning

confidence: 99%

“…There is a paucity of cases that describe both KC and ICE syndrome variants together. 6–9 In these reports, the clinical correlation of both disease entities was described and observed. However, we report the first case of successful use of corneal CXL to halt the progression of KC in a patient with concurrent ICE syndrome.…”

mentioning

confidence: 99%

Corneal Collagen Cross-Linking for Late Onset Progressive Keratoconus in Iridocorneal Endothelial Syndrome

Phylactou

Din

Aiello

et al. 2023

Cornea

View full text Add to dashboard Cite

show abstract

“…Cremona FA et al published a 10-year review of the concomitant presentation of KC with other corneal dystrophies, but no cases of keratoconus and ICE syndrome were reported [21]. In the literature, only a few cases of KC associated with one of the ICE syndrome variants have been reported [10–12].…”

Section: Discussionmentioning

confidence: 99%

“…Few cases of KC associated with ICE syndrome variants have been reported [10–12]. The herein case report describes the clinical features and the complex management of the rare association of KC and unilateral EIA.…”

Section: Introductionmentioning

confidence: 96%

Iridocorneal endothelial syndrome in a patient with keratoconus – a case report

et al. 2019

View full text Add to dashboard Cite

BackgroundTo describe a case of a rare association of bilateral keratoconus and unilateral essential iris atrophy and to conduct a literature review of the current strategies of treatment of the corneal disease and glaucoma in patients with Iridocorneal Endothelial Syndrome (ICE).Case presentationWe report a rare association of bilateral keratoconus and unilateral essential iris atrophy in a 38-year-old man. Diagnosis of bilateral keratoconus was confirmed by corneal topography. Slit-lamp examination showed extensive iris atrophy with corectopia and policoria in one eye. Corneal specular microscopy revealed an abnormal endothelium morphology in the same eye with extensive peripheral anterior synechiae and closure of the drainage angle at gonioscopy. Intraocular pressure was 26 mmHg, despite maximal topical therapy. Optic disc examination showed severe glaucomatous cupping. Surgery by glaucoma drainage device implantation was performed.ConclusionEssential iris atrophy is a rare clinical variant of ICE syndrome characterized by profound anatomical alterations of the anterior segment associated with corneal edema and secondary glaucoma. In these patients, selective keratoplasties have replaced penetrating keratoplasty to treat corneal decompensation and glaucoma drainage devices are preferred to conventional trabeculectomy for the treatment of secondary glaucoma.

show abstract

“…Few cases of bilateral KC and ICE syndrome have been reported. [ 3 - 6 ] This report describes the clinical features and management of a case of unilateral KC and ICE syndrome.…”

Section: Introductionmentioning

confidence: 99%

Unilateral keratoconus associated with iridocorneal endothelial syndrome: Case report

Kalantan

2023

Saudi J Ophthalmol

View full text Add to dashboard Cite

We report a rare association of unilateral keratoconus (KC) and iridocorneal endothelial syndrome in a 34-year-old female. Slit-lamp examination showed advanced KC with faint apical scarring in her right eye. The pupil was superiorly displaced with superior peripheral anterior synechia. Specular microscopy showed abnormal endothelium with low endothelial cell count in the right eye. Corneal topography confirmed the unilateral KC diagnosis. As the patient did not tolerate hard contact lens, penetrating keratoplasty with pupilloplasty was performed with excellent outcome.

show abstract

A unique case of keratoconus with Cogan-Reese syndrome and secondary glaucoma

Cited by 5 publications

References 10 publications

Corneal Collagen Cross-Linking for Late Onset Progressive Keratoconus in Iridocorneal Endothelial Syndrome

Corneal Collagen Cross-Linking for Late Onset Progressive Keratoconus in Iridocorneal Endothelial Syndrome

Iridocorneal endothelial syndrome in a patient with keratoconus – a case report

Unilateral keratoconus associated with iridocorneal endothelial syndrome: Case report

Contact Info

Product

Resources

About