A unilateral medial frontal cortical lesion impairs trial and error learning without visual control

Amiez, Céline; Champod, Anne Sophie; Wilson, Charles R.E.; Procyk, Emmanuel; Petrides, Michael

doi:10.1016/j.neuropsychologia.2015.06.022

Cited by 7 publications

(1 citation statement)

References 48 publications

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“…Subjects typically lacked sensitivity to noxious stimuli and did not initiate movements or speech. Damage to ACC in animals leads to a lack of willingness to exert more effort to obtain a larger reward , and in humans, damage to areas including ACC can lead to failures of internally guided action (Amiez, Sophie, Charles, Procyk, & Petrides, 2015). Obsessive compulsive disorder prominently entails overactivity of ACC (Fitzgerald et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

Foraging Value, Risk Avoidance, and Multiple Control Signals: How the Anterior Cingulate Cortex Controls Value-based Decision-making

Brown

Alexander

2017

Journal of Cognitive Neuroscience

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Recent work on the role of the ACC in cognition has focused on choice difficulty, action value, risk avoidance, conflict resolution, and the value of exerting control among other factors. A main underlying question is what are the output signals of ACC, and relatedly, what is their effect on downstream cognitive processes? Here we propose a model of how ACC influences cognitive processing in other brain regions that choose actions. The model builds on the earlier Predicted Response Outcome model and suggests that ACC learns to represent specifically the states in which the potential costs or risks of an action are high, on both short and long timescales. It then uses those cost signals as a basis to bias decisions to minimize losses while maximizing gains. The model simulates both proactive and reactive control signals and accounts for a variety of empirical findings regarding value-based decision-making.

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Section: Introductionmentioning

confidence: 99%