A Unified Potentiostat for Electrochemical Glucose Sensors

Abstract

A unified potentiostat circuit for both O 2 -and H 2 O 2 -based electrochemical glucose sensors was proposed and its function was verified by circuit simulations and measurement results of a fabricated chip. This circuit consisted of an operational amplifier, a comparator and current mirrors. The proposed circuit was fabricated with a 0.13 ㎛ thick oxide CMOS process and an active area of 360 ㎛ × 100 ㎛. The measurements revealed an input operation range from 0.5 V to 1.6 V in the H 2 O 2 -based bio-sensor and from 1.7 V to 2.6 V in the O 2 -based bio-sensor with a supply voltage of 3.3 V. The evaluation results showed that the proposed potentiostat circuit is suitable for measuring the electrochemical cell currents of both O 2 -and H 2 O 2 -based glucose sensors.

Current Fluctuation Measurements of Amperometric Gas Sensors Constructed with Three Different Technology Procedures

“…between the working and counter electrodes. Several different circuit topologies of potentiostat exist [27,35,36]. The measurement circuitry of potentiostat in the cooperating laboratory gave only preliminary estimation of current fluctuations, but the used apparatus presented a high level of engineering.…”

“…Generally, an amperometric sensor is the core component of a potentiostat circuit [27,35,36], which provides two main functions [27]: (i) controlling the voltage between the working and reference electrodes, and (ii) measuring the current flowing through the sensor, i.e. between the working and counter electrodes.…”

Flexible and Cellulose-based Organic Electronics

“…Figure 5.5 Schematic structure of a three-electrode electrochemical cell and a potentiostat. [144] An electrode which works close to an ideally non-polarizable electrode is of special interest for electrochemical measurements. If one such electrode is used in an electrochemical cell, then any change in the potential between the two electrodes must have occurred at the other electrode.…”