“…The measured values of parameters of dynamic instability differ (44,(59)(60)(61)(62)(63)(64)(65)(66)(67)(68), they depend on the cell phase (69,70), and on the distance from the cell membrane (71)(72)(73)(74). We take the following estimates from the literature: growth velocity vg = 0.1µms −1 (47,62,68,75) -although it might depend mildly on load and MT plus end location (52,72); shrinking velocity vs = 0.2µms −1 ; rescue rate (the transition rate from shrinkage to growth) rr = 0.044/s (59,61,76,77); and a length dependent catastrophe rate (transition rate from growth to shrinkage) cr(L) = exp((L − Lc)/bc) where Lc = πRCell + R Cell 2 , bc = (L0 − Lc)/ln(rc), L0 = πRCell and rc = 0.022s −1 , reflecting a lower catastrophy rate close to the MTOC and a higher one at the cell periphery (54,71,78). The MT length distribution resulting from the dynamic instability with aforementioned parameters is shown in Fig.…”