2024
DOI: 10.1371/journal.pone.0301809
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A unified classification system for HIV-1 5’ long terminal repeats

Xing Guo,
Dan Yu,
Mengying Liu
et al.

Abstract: The HIV-1 provirus mainly consists of internal coding region flanked by 1 long terminal repeats (LTRs) at each terminus. The LTRs play important roles in HIV-1 reverse transcription, integration, and transcription. However, despite of the significant study advances of the internal coding regions of HIV-1 by using definite reference classification, there are no systematic and phylogenetic classifications for HIV-1 5’ LTRs, which hinders our elaboration on 5’ LTR and a better understanding of the viral origin, s… Show more

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