A two‐centre experience of transanal total mesorectal excision

Buchs, Nicolas; Wynn, Greg; Austin, Ralph; Penna, Marta; Findlay, John M.; Bloemendaal, A. L. A.; Mortensen, Neil; Cunningham, Chris; Jones, Oliver; Guy, Richard; Hompes, Roel

doi:10.1111/codi.13394

Cited by 45 publications

(43 citation statements)

References 28 publications

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“…A total of 1581 duplicates were removed, and 1743 articles were excluded after screening title and reading abstract (performed by both CD and AT), leaving 165 articles for full-text review. Finally, 33 articles fulfilled all the inclusion criteria and met no exclusion criteria and were included for analyses [1, 15–18, 27–54]. These 33 articles comprised 3 case reports, 25 case series and 5 comparative studies (Fig.…”

Section: Resultsmentioning

confidence: 99%

Clinical outcomes and case volume effect of transanal total mesorectal excision for rectal cancer: a systematic review

et al. 2016

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Transanal total mesorectal excision (TaTME) has been developed to improve quality of TME for patients with mid and low rectal cancer. However, despite enthusiastic uptake and teaching facilities, concern exists for safe introduction. TaTME is a complex procedure and potentially a learning curve will hamper clinical outcome. With this systematic review, we aim to provide data regarding morbidity and safety of TaTME. A systematic literature search was performed in MEDLINE (PubMed), EMBASE (Ovid) and Cochrane Library. Case reports, cohort series and comparative series on TaTME for rectal cancer were included. To evaluate a potential effect of case volume, low-volume centres (n ≤ 30 total volume) were compared with high-volume centres (n > 30 total volume). Thirty-three studies were identified (three case reports, 25 case series, five comparative studies), including 794 patients. Conversion was performed in 3.0% of the procedures. The complication rate was 40.3, and 11.5% were major complications. The quality of the mesorectum was “complete” in 87.6%, and the circumferential resection margin (CRM) was involved in 4.7%. In low- versus high-volume centres, the conversion rate was 4.3 versus 2.7%, and major complication rates were 12.2 versus 10.5%, respectively. TME quality was “complete” in 80.5 versus 89.7%, and CRM involvement was 4.8 and 4.5% in low- versus high-volume centres, respectively. TaTME for mid and low rectal cancer is a promising technique; however, it is associated with considerable morbidity. Safe implementation of the TaTME should include proctoring and quality assurance preferably within a trial setting.

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Section: Resultsmentioning

confidence: 99%

Clinical outcomes and case volume effect of transanal total mesorectal excision for rectal cancer: a systematic review

et al. 2016

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“…Transanal TME (TaTME) is an innovative approach with the potential to overcome limitations encountered in low rectal cancer surgery. The feasibility, short‐term outcomes and effectiveness compared with other minimally invasive approaches have been described. However, there is paucity of data on quality of life (QoL) and functional outcomes after TaTME.…”

Section: Relationships Between Patient and Tumour Variables And Validmentioning

confidence: 99%

Patient-reported functional and quality-of-life outcomes after transanal total mesorectal excision

Keller

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Spinelli

et al. 2019

British Journal of Surgery

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“…Various techniques of proctocolectomy have been described and technical modifications continue to be made . We present a video and commentary for the intra‐abdominal component of laparoscopic panproctocolectomy.…”

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confidence: 99%