A twist six-membered rhodamine-based fluorescent probe for hypochlorite detection in water and lysosomes of living cells

Wang, Zechen; Zhang, Qinghao; Liu, Junwen; Sui, Ran; Li, Yahui; Li, Yue; Zhang, Xinfu; Yu, Haibo; Jing, Kui; Zhang, Mingyan; Xiao, Yi

doi:10.1016/j.aca.2019.07.046

Cited by 39 publications

(5 citation statements)

References 62 publications

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“…According to the previous works, ClO À solution with concentrations from 0 to 15 μM and lipopolysaccharide (LPS) were used to stimulate HUVEC as exogenous and endogenous ClO À , respectively (Figure 4b). [13][14] Observing through a home-built NIR-II microscopy, the consistent and relatively low NIR-II signal in PBS-treated living cells illustrated the high stability of the ANB-SHQ-6 sensor in the normal physiological microenvironment (Figure 4c, d). While the NIR-II signal intensity exhibited continuously fluorescence recovery along with the ClO À addition, exhibiting signal enhancement to 1.08, 1.57, and 1.90-fold under ClO À concentration 5 μM, 10 μM, and 15 μM, respectively, enabling the distinguishment of ClO À as low as 5 μM with significant differences (Fig- ure 4d, e, Figure S20).…”

Section: Methodsmentioning

confidence: 97%

NIR‐II Fluorescence Sensor Based on Steric Hindrance Regulated Molecular Packing for In Vivo Epilepsy Visualization

Zhao,

Lai,

et al. 2024

Angew Chem Int Ed

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Fluorescence sensing is crucial to study biological processes and diagnose diseases, especially in the second near‐infrared (NIR‐II) window with reduces background signals. However, it's still a great challenge to construct "off‐on" sensors when the sensing wavelength extends into the second near‐infrared (NIR‐II) region to obtain higher imaging contrast, mainly due to the difficult synthesis of spectral overlapped quencher. Here, we present a new fluorescence quenching strategy, which utilizes steric hindrance quenchers (SHQ) to tune the molecular packing state of fluorophores and suppress the emission signal. Density functional theory (DFT) calculations further reveal that large SHQ can competitively packing with fluorophores and prevent their self‐aggregation. Based on this quenching mechanism, a novel activatable "off‐on" sensing method is achieved via bio‐analyte responsive invalidation of SHQ, namely Steric Hindrance Invalidation geNerated Emission (SHINE) strategy. As a proof of concept, the ClO‐ sensitive SHQ lead to the bright NIR‐II signal release in epileptic mouse hippocampus under the skull and high photon scattering brain tissue, providing the real‐time visualization of ClO‐ generation process in living epileptic mice.

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Section: Methodsmentioning

confidence: 97%

NIR‐II Fluorescence Sensor Based on Steric Hindrance Regulated Molecular Packing for In Vivo Epilepsy Visualization

Zhao,

Lai,

et al. 2024

Angew Chem Int Ed

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“…In MB, biological signals are characteristically minor elements of certain nanometers to some micrometers in extent, including phospholipid vesicles and atoms, which are typically broadcast in gaseous. Associated with the radio broadcast, MB has definite benefits in micro and macro gage [30].…”

Section: Molecular Broadcastmentioning

confidence: 99%

6G and Blockchain Communication: Applications, Challenges, and Predictions

Singh¹,

Singh²,

Singh³

et al. 2023

IJCATR

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In today's era 5G network is being used globally, and research/technical officialdoms worldwide started work with 5G communication. But providing high-quality services (QoS) and power proficiency 6G communication is predictable in the network. This paper includes a comprehensive analysis of the development of 6G communication. In this paper, we have discussed diverse network generations with specifications and growths, detailed study of different technologies used in 6G communication has been elaborated. This chapter also deliberates on upcoming challenges in 6G communication for canvassers. Various 6G application areas are also presented in this survey. The critical focus is associated with 6G architecture which includes protocols stacks, coverage, and artificial intelligence. This paper aims to give informative direction for consequent 6G communication research.

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“…Currently, there are many screening methods such as polymerase chain reaction (PCR), chromatography-based proteomics technology (Feng et al, 2020;Dai et al, 2021). Nonetheless, these instruments are comparatively intricate, require a significant amount of time, and come with high costs, thereby restricting the widespread adoption of practical application and only able to measure the protein concentration (Chan et al, 2012;Du et al, 2020;Wang et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

Determination of Esterase Activity on Benzothiazole Based Probe In Biological Samples

Abdulhadi El-Ali,

Radhi

2023

Egyptian Academic Journal of Biological Sciences. C, Physiology

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A twist six-membered rhodamine-based fluorescent probe for hypochlorite detection in water and lysosomes of living cells

Cited by 39 publications

References 62 publications

NIR‐II Fluorescence Sensor Based on Steric Hindrance Regulated Molecular Packing for In Vivo Epilepsy Visualization

NIR‐II Fluorescence Sensor Based on Steric Hindrance Regulated Molecular Packing for In Vivo Epilepsy Visualization

6G and Blockchain Communication: Applications, Challenges, and Predictions

Determination of Esterase Activity on Benzothiazole Based Probe In Biological Samples

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