A Turning Point for Mood during Sleep Deprivation Therapy -does it Exist?

Hj, Haug; Fähndrich, E

doi:10.1055/s-2007-1017033

Cited by 6 publications

(1 citation statement)

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“…During this extended wake, a turning point of mood common to all patients has not been demonstrated, but existing studies suggest that the antidepressant effects of SD do not occur before the end of the night awake [31] and become clinically evident when the patient is exposed to daytime light, after the night awake, or earlier during the night, if the SD is carried out in bright light [32] .…”

Section: Duration Of Wakementioning

confidence: 99%

Sleep Deprivation in Mood Disorders

2011

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Growing clinical evidence in support of the efficacy and safety of sleep deprivation (SD), and its biological mechanisms of action suggest that this technique can now be included among the first-line antidepressant treatment strategies for mood disorders. SD targets the broadly defined depressive syndrome, and can be administered according to several different treatment schedules: total versus partial, single versus repeated, alone or combined with antidepressant drugs, mood stabilizers, or other chronotherapeutic techniques, such as light therapy and sleep phase advance. The present review focuses on clinical evidence about the place of SD in therapy, its indications, dosage and timing of the therapeutic wake, interactions with other treatments, precautions and contraindications, adverse reactions, mechanism of action, and comparative efficacy, with the aim of providing the clinical psychiatrist with an updated, concise guide to its application.

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Section: Duration Of Wakementioning

confidence: 99%