A Turn‐On Fluorescence Chemosensor for Cyanide in Aqueous Media Based on a Nucleophilic Addition Reaction

Abstract

We synthesized a new cyanide (CN  ) chemosensor CX based on a nucleophilic addition reaction prompted by cyanide ion, which could be used for highly selective and sensitive fluorescence turn-on detection of cyanide in aqueous media. The CX showed selective fluorescence recognition for CN  , the miscellaneous competitive anions (F  , Cl  , Br  , I  , AcO  , 2 4 H PO -, 4 HSO -, 4 ClO -, S 2 , 3 4 PO -, 2 3COand SCN  ) did not lead to any significant interference. The detection limit of the sensor towards CN − is 1.15×10 7 mol•L -1 . The sensor has been successfully applied to estimate the cyanide ion in seeds of cherries. Test strips based on CX were fabricated, which could be used as a convenient and efficient CN − test kit to detect CN − in aqueous solution for ''in-the-field'' measurement.

Determination of Cyanide in Water and Food Samples Using an Efficient Naphthalene-Based Ratiometric Fluorescent Probe

“…30 Nevertheless, most of the reported fluorescent probes for determining cyanide in water samples and food samples only displayed fluorescence turn-on response. 31−37 A major limitation of the fluorescence turn-on probe is that the signal output is vulnerable to factors such as excitation intensity, probe concentration, and instrumental efficiency. By contrast, a ratiometric fluorescent probe can effectively eliminate the above-mentioned limitations and consequently provide more accurate analysis.…”

“…Additionally, cyanide fluorescent probes have been developed on the basis of the specific nucleophilic reactivity of cyanide to electrophilic double bonds, such as CC, CO, CN, CS, or CN + . Nevertheless, most of the reported fluorescent probes for determining cyanide in water samples and food samples only displayed fluorescence turn-on response. − A major limitation of the fluorescence turn-on probe is that the signal output is vulnerable to factors such as excitation intensity, probe concentration, and instrumental efficiency. By contrast, a ratiometric fluorescent probe can effectively eliminate the above-mentioned limitations and consequently provide more accurate analysis. , In addition, the preparation of the reported probes generally needs sophisticated synthesis procedures.…”