“…The brain of the deaf-dumb-blind patient described by Gans (25) showed a decrease in the number of fibers in the occipital cortex and a decrease in size of the corpora geniculata externa. Although the case of Hoppe (31) was complicated, clinically and anatomically, by cerebellar and pontine disturbances, visual defects were present and these were associated with lesions of the corpora quadrigemina. The clinical symptoms in the patient described by Winkler (62) are of great interest, since vision for light was retained but recognition of shapes was lost.…”