A triple-helix molecular switch photoelectrochemical biosensor for ultrasensitive microRNA detection based on position-controllable CdS//CdTe signal enhancement and switching

Abstract

A triple-helix molecular switch photoelectrochemical biosensor is developed for ultrasensitive microRNA detection based on position-controllable CdS//CdTe signal enhancement and switching.

A Signal-Enhanced Regenerative Electrochemical Aptasensor for Amyloid-β Oligomers Based on Triple-Helix Aptamer Probe

“…The stability of TAP (six to eight bases) is the same as that of DAP (>=10 bases). 45,56 With only six base pairs, the rigidity and stability of the DAP structure were weaker than that of TAP resulting in the proximity of DAP to electrode and the generation of large DPV (curve c). The ΔE p of the blank sample was not obvious.…”

A Direct‐Contact Photocurrent‐Direction‐Switching Biosensing Platform Based on In Situ Formation of CN QDs/TiO2 Nanodiscs and Double‐Supported 3D DNA Walking Amplification

“…[17] However, these switching strategies based on CdS, CuO, zinc oxide, etc., not only are limited in their practical application due to their toxicity or poor photostability, also two switching materials usually need to be connected by biological elements (such as peptides, DNA, and antibodies) because of the nondirect contact, resulting in the increase of electron transfer path and the reduction of switching efficiency. [14][15][16][17][18][19][20][21][22][23][24] Therefore, designing a direct-contact and environmentally friendly photocurrentdirection-switching system is a worthy research.…”

Co9S8 nanoparticle-functionalized CdS nanoflowers for signal-off photoelectrochemical bioanalysis of carcinoembryonic antigens with hybridization chain reaction

“…due to its excellent light-capturing capacity in the visible light region and suitable energy band position. [21][22][23] Unfortunately, the insufficient separation of electron-hole pairs and the surface photocorrosion phenomenon that easily occurs under prolonged intense light irradiation restrict its further use. [22][23][24] Accordingly, a number of innovative strategies, such as modulating the morphologies, elemental doping, surface sensitization, and constructing heterostructures, have been explored to reduce the impact of the above-mentioned drawbacks on its performance.…”

“…[21][22][23] Unfortunately, the insufficient separation of electron-hole pairs and the surface photocorrosion phenomenon that easily occurs under prolonged intense light irradiation restrict its further use. [22][23][24] Accordingly, a number of innovative strategies, such as modulating the morphologies, elemental doping, surface sensitization, and constructing heterostructures, have been explored to reduce the impact of the above-mentioned drawbacks on its performance. 25,26 It is worth noting that the formation of heterostructures by combining two or more semiconductors is considered as one of the most straightforward approaches to improve the PEC properties.…”