A triple cascade approach towards the diastereoselective synthesis of spiro <i>trans</i>-decalinol scaffolds

Settipalli, Poorna Chandrasekhar; Anwar, Shaik

doi:10.1039/d2cc03562f

Chem. Commun.

2022

DOI: 10.1039/d2cc03562f

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A triple cascade approach towards the diastereoselective synthesis of spiro trans-decalinol scaffolds

Poorna Chandrasekhar Settipalli

Shaik Anwar

Abstract: A [2+2+2] annulation reaction between cyclohexanone, β-nitrostyrene and 2-arylidene-1,3-indanedione afforded the multisubstituted spiro trans-decalinol derivatives in high chemical yields in (upto 75%) and excellent diastereoselectivity (upto >20:1) at room temperature....

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Multicomponent reaction (MCR) for constructing bis-spirocyclohexane skeletons using β-nitrostyrene derived MBH acetates, 1,3-indanedione and aldehydes via [1 + 1 + 1 + 3] annulation

Gudise,

Anwar

2023

RSC Adv.

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Multicomponent reaction (MCR) for constructing bis-spirocyclohexane skeletons using β-nitrostyrene derived MBH acetates, 1,3-indanedione and aldehydes via [1 + 1 + 1 + 3] annulation

Gudise,

Anwar

2023

RSC Adv.

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A triple cascade approach towards the diastereoselective synthesis of spiro trans-decalinol scaffolds

Abstract: A [2+2+2] annulation reaction between cyclohexanone, β-nitrostyrene and 2-arylidene-1,3-indanedione afforded the multisubstituted spiro trans-decalinol derivatives in high chemical yields in (upto 75%) and excellent diastereoselectivity (upto >20:1) at room temperature....

Cited by 1 publication

References 67 publications

Multicomponent reaction (MCR) for constructing bis-spirocyclohexane skeletons using β-nitrostyrene derived MBH acetates, 1,3-indanedione and aldehydes via [1 + 1 + 1 + 3] annulation

Multicomponent reaction (MCR) for constructing bis-spirocyclohexane skeletons using β-nitrostyrene derived MBH acetates, 1,3-indanedione and aldehydes via [1 + 1 + 1 + 3] annulation

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