“…The incubation period in man appears generally to be twelve to thirteen days (Ferenbaugh et al, 1938), and the Bachman intradermal test-the most reliable form of early diagnosis, since eosinophilia and other features are not evident until larviposition has begun-does not -become positive until about sixteen days after infection at the earliest in man (Augustine and Theiler, 1932;Maternowska, 1933). Such a limited period of time during which serum would be of use for this purpose would make it of no significance in treatment unless methods of early diagnosis could be improved.…”