A trial of bran and bran biscuits for constipation in mentally handicapped and psychogeriatric patients

McCallum, G.; Ballinger, Brian R.; Presly, A. S.

doi:10.3109/09637487809143903

Cited by 9 publications

(8 citation statements)

References 1 publication

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“…54 One study involving 26 patients showed a nonsignificant increase in frequency with ispaghula compared with an herb mixture; and another study of 27 hospitalized psy-chiatric patients showed no differences between two preparations of bran and an irritant laxative (senna). 44,47 Five of 16 direct comparisons demonstrated that one agent was significantly superior to another in improving bowel movement frequency. One showed magnesium hydroxide, an osmotic laxative, increased frequency compared with a combination laxative containing a very small dose of sorbitol (osmotic) plus fiber.…”

Section: Bowel Movement Frequency Resultsmentioning

confidence: 99%

The Treatment of Chronic Constipation in Adults

et al. 1997

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OBJECTIVE: To evaluate whether laxatives and fiber therapies improve symptoms and bowel movement frequency in adults with chronic constipation. DATA SOURCES:English language studies were identified from computerized MEDLINE , Biological Abstracts (1990)(1991)(1992)(1993)(1994)(1995), and Micromedex searches; bibliographies; textbooks; laxative manufacturers; and experts.STUDY SELECTION: Randomized trials of laxative or fiber therapies lasting more than 1 week that evaluated clinical outcomes in adults with chronic constipation. MEASUREMENTS AND MAIN RESULTS:Two independent reviewers appraised each trial's characteristics including methodologic quality. There were 36 trials involving 1,815 persons from a variety of settings including clinics, hospitals and nursing homes. Twenty-three trials were 1 month or less in duration. Several laxative and fiber preparations were evaluated. Twenty trials had a placebo, usual care, or discontinuation of laxative control group, and 16 directly compared different agents. Laxatives and fiber increased bowel movement frequency by an overall weighted average of 1.4 (95% confidence interval [CI] 1.1-1.8) bowel movements per week. Fiber and bulk laxatives decreased abdominal pain and improved stool consistency compared with placebo. Most nonbulk laxative data concerning abdominal pain and stool consistency were inconclusive, though cisapride, lactulose, and lactitol improved consistency. Data concerning superiority of various treatments were inconclusive. No severe side effects for any of the therapies were reported. CONCLUSIONS:Both fiber and laxatives modestly improved bowel movement frequency in adults with chronic constipation. There was inadequate evidence to establish whether fiber was superior to laxatives or one laxative class was superior to another.

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Section: Bowel Movement Frequency Resultsmentioning

confidence: 99%

The Treatment of Chronic Constipation in Adults

et al. 1997

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“…The addition of dietary fibre and a liquid diet, which is usually impossible in ID, increases stool size and stool consistency, but transit times remains unchanged (Menardo et al 1987; Beuret‐Blaquart et al 1990; Nino‐Murcia et al 1990; Keshavarzian et al 1995). Improvement of bowel function in this population has also been achieved with polysaccharides (Liebl et al 1990) and bran (McCallum et al 1978; DeMorais et al 1996). Therefore, bran and adequate fluid intake should be increased as much as possible.…”

Section: Discussionmentioning

confidence: 96%

The prevalence of constipation in institutionalized people with intellectual disability

Böhmer

Taminiau

Klinkenberg‐Knol

et al. 2001

J intellect Disabil Res

106

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Constipation is a common problem in people with intellectual disability (ID). Laxatives are frequently prescribed with disappointing results. The prevalence of constipation was investigated in a random population of 215 people with ID (IQ < 50) and constipation was correlated with clinical symptoms. All subjects were scored for bowel habits. Constipation was defined as having a bowel movement less than three times a week or the necessity of using laxatives more than three times a week. Further possible accompanying factors were evaluated. The control subjects were defined as individuals who did not use laxatives. Subjects with constipation were defined as patients and were compared to subjects without constipation (controls). One hundred and forty-nine out of 215 cases (69.3%) showed constipation. Constipation was significantly correlated with non-ambulancy, cerebral palsy, the use of anticonvulsive medication or benzodiazepines, H2-receptor antagonists or proton pump inhibitors, food refusal, and an IQ < 35. Fifty-eight per cent of the patients used bisacodyl or magnesium oxide, 39% lactulose, 13% sodiumlaurylsulphoacetate/sodium citrate/sorbitol and only 10% were given sodium phosphate enemas. Faecal soiling was found in 15% of subjects, while manual evacuation of faeces was performed in nearly 7% of cases. Constipation was randomly demonstrated in almost 70% of the population with ID. Subjects with the above-mentioned accompanying factors are especially at risk for constipation. Contrary to the general population, constipation in people with ID is associated with little use of phosphate enemas, microlax, a low incidence of faecal soiling and manual evacuation of faeces, suggesting an aetiology without distal faecal impaction. The regimen and effect of therapy has to be studied to define adequate treatment schedules.

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“…54 One study involving 26 patients showed a nonsignificant increase in frequency with ispaghula compared with an herb mixture; and another study of 27 hospitalized psychiatric patients showed no differences between two preparations of bran and an irritant laxative (senna). 44,47 Five of 16 direct comparisons demonstrated that one agent was significantly superior to another in improving 52 This trial involved 64 nursing home patients and was not double-blind. Another single-blind trial among outpatients showed an irritant laxative (senna) combined with fiber (psyllium) increased bowel movement frequency more than fiber alone.…”

Section: Bowel Movement Frequency Resultsmentioning

confidence: 99%

The Treatment of Chronic Constipation in Adults A Systematic Review

et al. 1997

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OBJECTIVE:To evaluate whether laxatives and fiber therapies improve symptoms and bowel movement frequency in adults with chronic constipation. CONCLUSIONS: Both fiber and laxatives modestly improved bowel movement frequency in adults with chronic constipation. There was inadequate evidence to establish whether fiber was superior to laxatives or one laxative class was superior to another. DATA SOURCES:

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A trial of bran and bran biscuits for constipation in mentally handicapped and psychogeriatric patients

Cited by 9 publications

References 1 publication

The Treatment of Chronic Constipation in Adults

The Treatment of Chronic Constipation in Adults

The prevalence of constipation in institutionalized people with intellectual disability

The Treatment of Chronic Constipation in Adults A Systematic Review

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