A Trend in Sudden Sensorineural Hearing Loss: Data from a Population-Based Study

Kim, Shin Hye; Kim, Su Jong; Im, Hwibin; Kim, Tae Hun; Song, Jae Jun; Chae, Sung Won

doi:10.1159/000485313

Cited by 35 publications

(33 citation statements)

References 21 publications

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“…It remains unclear why female patients with CKD exhibited a significantly increased risk of SSNHL. However, another population-based study in South Korea showed that SSNHL has a slight female preponderance 24 ; thus, we thought our finding may be due to this different sex preponderance.…”

Section: Discussionmentioning

confidence: 63%

Chronic kidney disease is associated with increased risk of sudden sensorineural hearing loss and Ménière’s disease: a nationwide cohort study

Kim

Lee

Cha

et al. 2021

Sci Rep

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Several studies have demonstrated the harmful effects of chronic kidney disease (CKD) on the audiovestibular system. Through a time-to-event analysis, we aimed to compare the association of CKD with sudden sensorineural hearing loss (SSNHL), and Ménière’s disease against a control population without CKD. We used a total of 1,025,340 patients from the Korean National Health Insurance Service database from 2002 to 2013. The CKD group (n = 2572) included patients diagnosed with CKD more than three times between January 2003 and December 2005. The non-CKD group (n = 5144) consisted of two patients without CKD for every patient with CKD. Each patient was monitored until December 2013. We calculated the incidence, survival rate, and hazards ratio (HR) of SSNHL and Ménière’s disease. In the CKD group, the incidence of SSNHL and Ménière’s disease was 1.39 and 3.64 per 1000 person-years, respectively. Patients with CKD showed an adjusted HR of 2.15 and 1.45 for SSNHL and Ménière’s disease, respectively. Middle-aged patients with CKD were associated with a higher incidence of developing SSNHL and Ménière’s disease than those without CKD. Female patients with CKD had a higher risk of developing SSNHL; however, there was no significant difference in the risk of Ménière’s disease in patients with CKD according to sex. Our findings suggest that CKD is associated with an increased incidence of SSNHL and Ménière’s disease. Therefore, audiovestibular surveillance should be considered in patients with CKD.

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Section: Discussionmentioning

confidence: 63%

Chronic kidney disease is associated with increased risk of sudden sensorineural hearing loss and Ménière’s disease: a nationwide cohort study

Kim

Lee

Cha

et al. 2021

Sci Rep

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“…SSNHL is usually unilateral, with bilateral involvement accounting for less than 5% of the cases [ 3 ]. Recent population-based studies reported that the incidence of SSNHL ranges from 5 to 27 per 100,000 with a rapidly increasing annual incidence [ 4 , 5 ]. The inner ear hair cells are mainly responsible for transducing sound vibrations into electrical impulses, and then these electrical signals are transmitted by spiral ganglion neurons (SGNs) into the brainstem to have the hearing function [ 6 – 10 ].…”

Section: Introductionmentioning

confidence: 99%

Altered Brain Activity and Functional Connectivity in Unilateral Sudden Sensorineural Hearing Loss

Chen

Qin

et al. 2020

Neural Plasticity

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Background. Sudden sensorineural hearing loss (SSNHL) is an otologic emergency and could lead to social difficulties and mental disorders in some patients. Although many studies have analyzed altered brain function in populations with hearing loss, little information is available about patients with idiopathic SSNHL. This study is aimed at investigating brain functional changes in SSNHL via functional magnetic resonance imaging (fMRI). Methods. Thirty-six patients with SSNHL and thirty well-matched normal hearing individuals underwent resting-state fMRI. Amplitude of low-frequency fluctuation (ALFF), fractional ALFF (fALFF), and functional connectivity (FC) values were calculated. Results. In the SSNHL patients, ALFF and fALFF were significantly increased in the bilateral putamen but decreased in the right calcarine cortex, right middle temporal gyrus (MTG), and right precentral gyrus. Widespread increases in FC were observed between brain regions, mainly including the bilateral auditory cortex, bilateral visual cortex, left striatum, left angular gyrus (AG), bilateral precuneus, and bilateral limbic lobes in patients with SSNHL. No decreased FC was observed. Conclusion. SSNHL causes functional alterations in brain regions, mainly in the striatum, auditory cortex, visual cortex, MTG, AG, precuneus, and limbic lobes within the acute period of hearing loss.

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“…Approximately 27 per 100,000 persons suffer from SSNHL in the United States each year. In Korea, the incidence of SSNHL was estimated to be approximately 17.76 per 100,000 persons per year 10 . The cause of SSNHL is elusive and multifactorial.…”

Section: Introductionmentioning

confidence: 99%

Air pollution increases the risk of SSNHL: A nested case-control study using meteorological data and national sample cohort data

Choi

Min

Kim

2019

Sci Rep

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This study aimed to evaluate the impact of weather conditions and air pollution on the onset of sudden sensorineural hearing loss (SSNHL). The Korean Health Insurance Review and Assessment Service - National Sample Cohort (HIRA-NSC) from 2002 through 2013 was used. A total of 5,200 participants with SSNHL were matched 1:4 for age, sex, income, region of residence, hypertension, diabetes, and dyslipidemia with 20,800 control participants. Meteorological data included daily mean temperature (°C), daily highest temperature (°C), daily lowest temperature (°C), daily temperature difference (°C), relative humidity (%), ambient atmospheric pressure (hPa), pressure, SO 2 (ppm), NO 2 (ppm), O 3 (ppm), CO (ppm), and PM 10 (μg/m 3 ) of a mean of 60 days, 30 days, 14 days, 7 days, and 3 days before SSNHL were analyzed. Hourly measurements were taken from 94 places to assess the temperature, humidity, and atmospheric pressure and from 273 places to determine SO 2 , NO 2 , O 3 , CO, and PM 10 . Crude and adjusted odds ratios (ORs) and 95% confidence intervals (CIs) of meteorological data for SSNHL were analyzed using unconditional logistic regression analyses. Subgroup analyses were conducted by age and sex. The mean NO 2 and O 3 concentrations 14 days before the index date were different in the SSNHL group compared to those in the control group (P < 0.001 for NO 2 and P = 0.021 for O 3 ). The adjusted 14-day OR for NO 2 (0.1 ppm) exposure was 3.12 in the SSNHL group compared to that in the control group (95% CI = 2.16–4.49, P < 0.001). The increased odds of NO 2 exposure for 14 days in the SSNHL group persisted in the age group older than 30 years for both sexes. Other meteorological conditions did not show differences between the SSNHL and control groups. SSNHL was associated with high concentrations of NO 2.

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A Trend in Sudden Sensorineural Hearing Loss: Data from a Population-Based Study

Cited by 35 publications

References 21 publications

Chronic kidney disease is associated with increased risk of sudden sensorineural hearing loss and Ménière’s disease: a nationwide cohort study

Chronic kidney disease is associated with increased risk of sudden sensorineural hearing loss and Ménière’s disease: a nationwide cohort study

Altered Brain Activity and Functional Connectivity in Unilateral Sudden Sensorineural Hearing Loss

Air pollution increases the risk of SSNHL: A nested case-control study using meteorological data and national sample cohort data

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