A translational repression reporter assay for the analysis of RNA-binding protein consensus sites

Rationally designed stapled peptides allosterically inhibit PTBP1–RNA-binding

“… 1 We evaluated P-6 in competitive fluorescence polarization assays using previously described RNAs recognized by these proteins. 59 In both cases, no inhibition was observed up until 1 mM peptide concentrations ( Fig. 3C and S6 † ).…”