Abstract:The iris controls the level of retinal illumination by controlling pupil diameter. It is a site of diverse ophthalmological diseases, and it is a potential source of cells for ocular auto-transplantation. The present study provides foundational data on the mouse iris based on single nucleus RNA sequencing. More specifically, this work has (1) defined all of the major cell types in the mouse iris and ciliary body, (2) led to the discovery of two types of iris stromal cells and two types of iris sphincter cells,… Show more
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