A tough, antibacterial and antioxidant hydrogel dressing accelerates wound healing and suppresses hypertrophic scar formation in infected wounds

Hydrogel-exosome system in tissue engineering: A promising therapeutic strategy

“… [ 174 ] Tannic acid Hypertrophic scar Dual-network hydrogel composed of agarose. [ 157 ] PAM-based Sulfamethoxazole Full-thickness skin defect Chitosan semi-interpenetrating polymer network. [ 162 ] PEG-based Bone Morphogenetic Protein-2 Skull defect Dual-network structure composed of thiolated chitosan.…”

“…This multifunctional hydrogel demonstrates excellent therapeutic effects in hypertrophic scar models. Moreover, due to its common raw materials and simple preparation methods, this hydrogel is highly suitable for large-scale production, with broad prospects for translation [ 157 ]. However, in the field of cartilage regeneration, PVA-based hydrogels often face challenges in simultaneously achieving lubrication performance and mechanical strength.…”

Screening of Short-Chain Antimicrobial Peptide LKARI with Broad-Spectrum Bactericidal Properties and Its Application in Promoting Wound Healing

“…Soft and elastic, it can relieve pain. The breathing and bacteriostatic nature helps in decreasing the occurrence of wound infection. , Over the past few years, research on wound dressings has focused on transparent wound observation and the creation of an appropriate moist environment to promote healing. ,, The PVA-based hydrogel exhibits exceptional toughness, as stated in research studies. , SA possesses hemostatic properties that can be easily removed. , …”

“…15,18,19 The PVA-based hydrogel exhibits exceptional toughness, as stated in research studies. 20,21 SA possesses hemostatic properties that can be easily removed. 22,23 The aim of this study was to develop a short-chain antibacterial peptide known as LKARI.…”