Polylactic acid (PLA) is often applicable in biomedical because in environment it degrades into carbon dioxide and water. This study aims to prepare sandwich-structure PLA/ Tencel composite nonwoven, following by its property test for evaluating effect on wound dressing. In this study, PLA fibers, blended with Tencel fibers, were made into nonwoven fabrics based on nonwoven processing technology. After that, their tensile strength, tearing strength and softness were tested for evaluating nonwoven fabric properties. The result displays that, PLA nonwoven fabrics show higher tensile strength and tearing strength than Tencel nonwoven fabrics.