A thymic carcinoid mimicking acute aortic dissection

Vohra, Hunaid A.; Alzetani, Aiman; Guha, Tanya; Rosin, Michael

doi:10.1016/s0967-2109(02)00141-2

Cited by 3 publications

(1 citation statement)

References 3 publications

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“…The event in our patient, noticed by marked ECG findings, seems to be rare, with only two reports describing ECG changes in relation to serotonin-producing carcinoid tumors [9, 10]. It is believed that serotonin may affect coronary spasms, mimicking acute coronary syndrome with typical ECG changes, which may even lead to coronary stent placement and balloon dilatation.…”

Section: Discussionmentioning

confidence: 73%

Tricuspid Valve Regurgitation as a Presenting Symptom of Metastasized Carcinoid Tumor

Engelsman¹,

Duijvendijk²,

Groenemeijer³

et al. 2012

Case Rep Gastroenterol

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A 66-year-old woman was diagnosed with hepatic metastasized carcinoid tumor of the ileocecal junction resulting in elevated plasma chromogranin A levels and urinary 5-hydroxyindoleacetic acid (5-HIAA) levels. Further examination showed right-sided heart failure with severe tricuspid valve regurgitation. Carcinoid tumors produce serotonin which leads to flushing, secretory diarrhea, bronchospasm and hypotension, known as carcinoid syndrome. Serotonin is metabolized to 5-HIAA, which is inactive, in the liver and the lungs. However, hepatic metastases may result in direct exposure of the heart to serotonin, which induces plaque-like deformities on the tricuspid valve, and in turn induces valve regurgitation. This condition is known as carcinoid heart disease. Tricuspid valve regurgitation may induce risk of massive blood loss in case of liver surgery through high-volume backflow in the hepatic veins. This report shows the clinical relevance of carcinoid heart disease in the perioperative setting.

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Section: Discussionmentioning

confidence: 73%

Tricuspid Valve Regurgitation as a Presenting Symptom of Metastasized Carcinoid Tumor

Engelsman¹,

Duijvendijk²,

Groenemeijer³

et al. 2012

Case Rep Gastroenterol

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Acute Aortic Dissection in the Emergency Department: Diagnostic Challenges and Evidence-Based Management

Upadhye

Schiff

2012

Emergency Medicine Clinics of North America

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Sequential Radial Artery Grafting Three-Vessel Coronary Artery Disease

Akinci

Erentuğ

Uzun

et al. 2005

Asian Cardiovasc Thorac Ann

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Our objective was to compare the results of revascularization by sequential radial artery (RA) grafting with a left anterior descending left internal mammary artery (LIMA)-RA t-composite grafting technique. Patients were grouped as those with proximal anastomoses performed on the ascending aorta (Group A; n = 38), and those with proximal anastomoses performed on the LIMA as t-grafts (Group T; n = 13). Neither of the two groups revealed any mortality. The average number of grafts was lower in Group T (2.23 +/- 0.43 in group T and 2.85 +/- 0.69 in group A, p < 0.05). The results of the control coronary artery angiographies were superior in Group A. The patency rate of the RA grafts was 96.8% in Group A. Of the 20 distal anastomoses performed with RA grafts in 8 patients from Group T, nine (45%) were found to be patent. The patency rates of RA grafts with sequential distal anastomoses were found to be better when the proximal anastomosis was performed on the ascending aorta rather than on the LIMA. In conclusion, sequential distal anastomosis of RA grafts seem to be safe and effective when proximal anastomoses are performed on the ascending aorta.

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A thymic carcinoid mimicking acute aortic dissection

Cited by 3 publications

References 3 publications

Tricuspid Valve Regurgitation as a Presenting Symptom of Metastasized Carcinoid Tumor

Tricuspid Valve Regurgitation as a Presenting Symptom of Metastasized Carcinoid Tumor

Acute Aortic Dissection in the Emergency Department: Diagnostic Challenges and Evidence-Based Management

Sequential Radial Artery Grafting Three-Vessel Coronary Artery Disease

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